Compile Data Set for Download or QSAR
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Found 73 with Last Name = 'honores' and Initial = 'ee'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317227((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317230((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317229((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317231((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-((d...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317243((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(di...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317244((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317232((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(3-((d...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187989(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((di...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187985(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-((di...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187975(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187984(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187981(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((di...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317235((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187987(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-((di...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187977(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-((di...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187983(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-(2-(...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317236((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317228((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317234((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187976(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187980(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(3-((di...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317239((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-mor...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187978(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-((di...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187979(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-((di...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317237((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187982(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((di...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317230((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187986(7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethyny...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317231((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-((d...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317240((E)-4-(2,4-dichlorophenylamino)-7-(4-morpholinobut...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317233((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317229((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317243((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(di...)
Affinity DataIC50:  62nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317227((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317244((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187984(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50:  81nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187989(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((di...)
Affinity DataIC50:  86nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187983(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-(2-(...)
Affinity DataIC50:  87nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317232((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(3-((d...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187988(7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)ethyny...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187981(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((di...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187975(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317238((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187985(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(5-((di...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317235((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187977(4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(4-((di...)
Affinity DataIC50:  190nMAssay Description:Inhibition of Src dependent proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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