Affinity DataKi: 0.00200nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.00500nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.00700nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.00800nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0110nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0110nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0120nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0190nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0220nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0240nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0260nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0480nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0960nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 0.630nM ΔG°: -52.0kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
TargetThreonine--tRNA ligase 1, cytoplasmic(Homo sapiens (Human))
Trius Therapeutics
Curated by ChEMBL
Trius Therapeutics
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -50.2kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nM ΔG°: -49.4kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
TargetThreonine--tRNA ligase 1, cytoplasmic(Homo sapiens (Human))
Trius Therapeutics
Curated by ChEMBL
Trius Therapeutics
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nM ΔG°: -48.9kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -48.6kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -48.3kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric analysis in p...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.2kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
TargetThreonine--tRNA ligase 1, cytoplasmic(Homo sapiens (Human))
Trius Therapeutics
Curated by ChEMBL
Trius Therapeutics
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nM ΔG°: -48.0kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
TargetThreonine--tRNA ligase 1, cytoplasmic(Homo sapiens (Human))
Trius Therapeutics
Curated by ChEMBL
Trius Therapeutics
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
TargetThreonine--tRNA ligase 1, cytoplasmic(Homo sapiens (Human))
Trius Therapeutics
Curated by ChEMBL
Trius Therapeutics
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of Staphylococcus aureus DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair