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Found 272 with Last Name = 'hwang' and Initial = 'hj'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138204(US8871778, 161)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138201(US8871778, 144)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138210(US8871778, 189)
Affinity DataIC50:  1nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50:  1nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50:  1.70nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124761(CHEMBL3622935)
Affinity DataIC50:  1.90nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124705(CHEMBL3622924)
Affinity DataIC50:  2.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124709(CHEMBL3622928)
Affinity DataIC50:  3.5nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124756(CHEMBL3622934)
Affinity DataIC50:  3.70nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124765(CHEMBL3622938)
Affinity DataIC50:  5nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124707(CHEMBL3622926)
Affinity DataIC50:  5.40nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124807(CHEMBL3622944)
Affinity DataIC50:  5.70nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124711(CHEMBL3622930)
Affinity DataIC50:  6.20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124816(CHEMBL3622945)
Affinity DataIC50:  6.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124771(CHEMBL3622940)
Affinity DataIC50:  7.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124710(CHEMBL3622929)
Affinity DataIC50:  7.30nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124839(CHEMBL3622946)
Affinity DataIC50:  7.90nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124869(CHEMBL3622960)
Affinity DataIC50:  8nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124806(CHEMBL3622943)
Affinity DataIC50:  8.90nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124866(CHEMBL3622953)
Affinity DataIC50:  9.20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124781(CHEMBL3622942)
Affinity DataIC50:  12nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124763(CHEMBL3622936)
Affinity DataIC50:  13nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124778(CHEMBL3622941)
Affinity DataIC50:  14nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124769(CHEMBL3622939)
Affinity DataIC50:  17nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124764(CHEMBL3622937)
Affinity DataIC50:  18nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124865(CHEMBL3622951)
Affinity DataIC50:  20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50193253(CHEMBL3961676)
Affinity DataIC50:  20nMAssay Description:Inhibition of fluorescien-conjugated coactivator PGC1a binding to GST-tagged human ERRgamma LBD after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138203(US8871778, 160)
Affinity DataIC50:  20nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50193253(CHEMBL3961676)
Affinity DataIC50:  20nMAssay Description:Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 10 |...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124867(CHEMBL3622954)
Affinity DataIC50:  23nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50550304(CHEMBL4744529)
Affinity DataIC50:  26nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50550294(CHEMBL4791981)
Affinity DataIC50:  30nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50550305(CHEMBL4792390)
Affinity DataIC50:  34nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138221(US8871778, 52)
Affinity DataIC50:  37nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124708(CHEMBL3622927)
Affinity DataIC50:  38nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50:  38nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124713(CHEMBL3622932)
Affinity DataIC50:  39nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138210(US8871778, 189)
Affinity DataIC50:  44nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50193253(CHEMBL3961676)
Affinity DataIC50:  48nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) expressed in human AD293 cells after 24 hrs by beta-galactosidase/luciferase reporter gene assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485074(US10934303, Cmpd No. 38b | US10934303, Example 107...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124868(CHEMBL3622958)
Affinity DataIC50:  56nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50193250(CHEMBL3897416)
Affinity DataIC50:  58nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) expressed in human AD293 cells after 24 hrs by beta-galactosidase/luciferase reporter gene assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124841(CHEMBL3622947)
Affinity DataIC50:  61nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM50550299(CHEMBL4791571)
Affinity DataIC50:  64nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485045(US10934303, Cmpd No. 6e | US10934303, Example 5 | ...)
Affinity DataIC50:  67nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM138200(US8871778, 141)
Affinity DataIC50:  68nMT: 2°CAssay Description:Inhibition of human RET pre-incubated for 30 mins at room temperature before substrate addition and measured 1 hr after substrate addition by cell fr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485046(US10934303, Cmpd No. 6f | US10934303, Example 6 | ...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124712(CHEMBL3622931)
Affinity DataIC50:  72nMT: 2°CAssay Description:Inhibition of purified full-length human SYK pre-incubated for 30 mins at room temperature before Ulight-TK peptide substrate addition and measured 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kangwon National University

Curated by ChEMBL
LigandPNGBDBM50124705(CHEMBL3622924)
Affinity DataIC50:  77nMAssay Description:Inhibition of SYK-mediated TNFalpha production in human IgG-stimulated human THP1 cells incubated for 18 hrs by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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