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Found 72 with Last Name = 'ismail' and Initial = 't'
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  850nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110324(CHEMBL3605424)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175278((E)-2,3-bis(4-Hydroxyphenyl)acrylonitrile (21))
Affinity DataIC50:  5.06E+3nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110322(CHEMBL3605426)
Affinity DataIC50:  5.31E+3nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110325(CHEMBL3605423)
Affinity DataIC50:  6.71E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110253(CHEMBL3605418)
Affinity DataIC50:  9.52E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  1.08E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175269(Trans-4-Styryl-phenol (8))
Affinity DataIC50:  1.74E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110315(CHEMBL3605436)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110320(CHEMBL3605430)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110326(CHEMBL3605422)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110323(CHEMBL3605425)
Affinity DataIC50:  4.48E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175267(Trans-4-Styrylbenzonitrile (6))
Affinity DataIC50:  5.00E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175271(Trans-1-fluoro-4-(4-methoxystyryl)benzene (10))
Affinity DataIC50:  5.00E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175272(Trans-2-Bromo-1-methoxy-4-styryl-benzene (11))
Affinity DataIC50:  5.62E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110314(CHEMBL3605437)
Affinity DataIC50:  7.59E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110321(CHEMBL3605428)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175263(Trans-1-Fluoro-4-styryl-benzene (2))
Affinity DataIC50:  7.94E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110280(CHEMBL3605421)
Affinity DataIC50:  8.14E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110252(CHEMBL3605419)
Affinity DataIC50:  8.92E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110253(CHEMBL3605418)
Affinity DataIC50:  9.97E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110269(CHEMBL3605312)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110316(CHEMBL3605434)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110255(CHEMBL3605316)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110254(CHEMBL3605317)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110278(CHEMBL3605309)
Affinity DataIC50:  1.11E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110261(CHEMBL3605313)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110270(CHEMBL3605311)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110316(CHEMBL3605434)
Affinity DataIC50:  1.24E+5nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110279(CHEMBL3605308)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110252(CHEMBL3605419)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110255(CHEMBL3605316)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110257(CHEMBL3605314)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110329(CHEMBL3605427)
Affinity DataIC50:  1.41E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110325(CHEMBL3605423)
Affinity DataIC50:  1.51E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110251(CHEMBL3605420)
Affinity DataIC50:  1.52E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110318(CHEMBL3605432)
Affinity DataIC50:  1.61E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110317(CHEMBL3605433)
Affinity DataIC50:  1.61E+5nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175275(Trans-9-Styryl-anthracene (15))
Affinity DataIC50:  1.66E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110327(CHEMBL3605435)
Affinity DataIC50:  1.68E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110324(CHEMBL3605424)
Affinity DataIC50:  1.88E+5nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110277(CHEMBL3605310)
Affinity DataIC50:  1.88E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110319(CHEMBL3605431)
Affinity DataIC50:  1.88E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110314(CHEMBL3605437)
Affinity DataIC50:  2.52E+5nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110322(CHEMBL3605426)
Affinity DataIC50:  2.61E+5nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 30 mins before substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175279((E)-2-(4-Hydroxyphenyl)-3-(pyridin-3-yl)acrylonitr...)
Affinity DataIC50:  2.70E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175277((E)-3-(4-Methoxyphenyl)-2-phenylpropenal (20))
Affinity DataIC50:  2.76E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute of Integrative Medicine

LigandPNGBDBM175265(Trans-1-Bromo-4-styrylbenzene (4))
Affinity DataIC50:  2.77E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of The Punjab

Curated by ChEMBL
LigandPNGBDBM50110256(CHEMBL3605315)
Affinity DataIC50:  2.97E+5nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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