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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217627(CHEMBL110061)

IC50: 0.700nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217626(CHEMBL322538)

IC50: 0.700nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217801(CHEMBL111250)

IC50: 1nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217622(CHEMBL443539)

IC50: 1nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50144535((2S,3R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-...)

IC50: 1nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217599(CHEMBL109888)

IC50: 1nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50221046(CHEMBL72282)

IC50: <1.70nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217818(CHEMBL440515)

IC50: <1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217822(CHEMBL111173)

IC50: <1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217823(CHEMBL111630)

IC50: <1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217817(CHEMBL326209)

IC50: <1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50120387((2S,3R)-3-((R)-1-Carbamimidoyl-piperidin-3-ylmethy...)

IC50: <1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217824(BMS-363130 | CHEMBL70738)

IC50: <1.70nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217824(BMS-363130 | CHEMBL70738)

IC50: <1.70nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50120387((2S,3R)-3-((R)-1-Carbamimidoyl-piperidin-3-ylmethy...)

IC50: <1.70nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50144532((2S,3R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-...)

IC50: 1.80nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217819(CHEMBL109504)

IC50: 1.90nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217628(CHEMBL107493)

IC50: 3nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217813(CHEMBL302058)

IC50: 4nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217624(CHEMBL321622)

IC50: 4nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)

IC50: 4nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)

IC50: 4nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217813(CHEMBL302058)

IC50: 4nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50220841(BMS-262084 | CHEMBL71037)

IC50: 4nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217820(CHEMBL447534)

IC50: 4.60nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217623(CHEMBL109947)

IC50: 5nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217805(CHEMBL111548)

IC50: 5.20nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217601(CHEMBL320744)

IC50: 6nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

PDB
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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217601(CHEMBL320744)

IC50: 6nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

PDB
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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217815(CHEMBL113591)

IC50: 6nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

PDB
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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217625(CHEMBL326480)

IC50: 7nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50220827(CHEMBL441447)

IC50: 7nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

PDB
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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217629(CHEMBL111270)

IC50: 9nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

PDB
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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217800(CHEMBL109254)

IC50: 9nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

PDB
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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217816(CHEMBL432835)

IC50: 9nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

PDB
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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217811(CHEMBL109882)

IC50: 11nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217821(CHEMBL109733)

IC50: 12nMAssay Description:Inhibitory concentration against human tryptaseMore data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217600(CHEMBL109602)

IC50: 13nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

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Tryptase delta(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50217808(CHEMBL111141)

IC50: 18nMAssay Description:In vitro inhibition of human tryptase.More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50220830(CHEMBL306696)

IC50: 19nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)

IC50: 29nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50220737(CHEMBL308109)

IC50: 30nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb

BDBM686(BMS-186318 analog 23 | [1S-[1R*,2S*(2S*,3R*)]]-[3-...)

IC50: 30nMpH: 5.5 T: 2°CAssay Description:IC50 values are determined by inhibition of the cleavage of the peptidic substrate [V-S-Q-N-(beta-naphthylalanine)-P-I-V]. The IC50 value represents ...More data for this Ligand-Target Pair

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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50221047(CHEMBL70529)

IC50: 32nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50220837(CHEMBL70666)

IC50: 34nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

BDBM50220831(CHEMBL70964)

IC50: 39nMAssay Description:Inhibitory activity of compound against human tryptase was determinedMore data for this Ligand-Target Pair

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Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb

BDBM680((phenylmethyl)propyl]carbamic Acid, 1,1-Dimethylet...)

IC50: 40nMpH: 5.5 T: 2°CAssay Description:IC50 values are determined by inhibition of the cleavage of the peptidic substrate [V-S-Q-N-(beta-naphthylalanine)-P-I-V]. The IC50 value represents ...More data for this Ligand-Target Pair

Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb

BDBM679(BMS-186318 analog 16 | [1S-[1R*,2S*(2S*,3R*)]]-[3-...)

Dimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb

BDBM676(BMS-186318 analog 13 | [1S-[1R*, 2S*(2S*, 3R*)]-[3...)

IC50: 49nMpH: 5.5 T: 2°CAssay Description:IC50 values are determined by inhibition of the cleavage of the peptidic substrate [V-S-Q-N-(beta-naphthylalanine)-P-I-V]. The IC50 value represents ...More data for this Ligand-Target Pair