TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of Equus caballus BChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of electric eel AChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of AChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's metho...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of electric eel AChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT (neurotensin) as tracerMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of AChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 211nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of electric eel AChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 234nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
Affinity DataIC50: 336nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
Affinity DataIC50: 358nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of AChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's metho...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of electric eel AChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Lisbon
Curated by ChEMBL
University Of Lisbon
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of electric eel AChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 607nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
TargetNeurotensin receptor type 1(Rattus norvegicus)
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:IC50 was measured as binding to rat cortex membranes using [3H]- NT(neurotensin) as tracerMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of AChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's metho...More data for this Ligand-Target Pair