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Found 333 with Last Name = 'kirchhoff' and Initial = 'pd'
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582737(CHEMBL5076146)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToxopain-2(Toxoplasma gondii)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271690(CHEMBL222649)
Affinity DataIC50:  2nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582744(CHEMBL5085940)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582751(CHEMBL5094183)
Affinity DataIC50:  2.70nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582746(CHEMBL5081367)
Affinity DataIC50:  2.70nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582738(CHEMBL5071412)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582747(CHEMBL5079678)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582735(CHEMBL5090509)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582749(CHEMBL5079839)
Affinity DataIC50:  3nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271690(CHEMBL222649)
Affinity DataIC50:  3nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582734(CHEMBL5088651)
Affinity DataIC50:  3.20nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582740(CHEMBL5088354)
Affinity DataIC50:  3.40nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582739(CHEMBL5082413)
Affinity DataIC50:  3.5nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582736(CHEMBL5075855)
Affinity DataIC50:  3.5nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582743(CHEMBL5086858)
Affinity DataIC50:  3.60nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582750(CHEMBL5083305)
Affinity DataIC50:  3.70nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582748(CHEMBL5081374)
Affinity DataIC50:  3.80nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582741(CHEMBL5087485)
Affinity DataIC50:  4nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582753(CHEMBL5081163)
Affinity DataIC50:  4.20nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582752(CHEMBL5085064)
Affinity DataIC50:  4.60nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582742(CHEMBL5076001)
Affinity DataIC50:  6.90nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173310(CHEMBL3808660 | US10023564, Example 1)
Affinity DataIC50:  11nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173307(CHEMBL3809796 | US10023564, Example 8)
Affinity DataIC50:  12nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50355756(CHEMBL1909658)
Affinity DataIC50:  13nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271681(CHEMBL4129611)
Affinity DataIC50:  15nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50355755(CHEMBL1911296)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173315(CHEMBL3809100 | US10023564, Example 4)
Affinity DataIC50:  21nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50355751(CHEMBL1911286)
Affinity DataIC50:  21nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173305(CHEMBL3810107 | US10023564, Example 3)
Affinity DataIC50:  23nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50582745(CHEMBL5084863)
Affinity DataIC50:  42nMAssay Description:Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271692(CHEMBL4126611)
Affinity DataIC50:  42nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM31993(Dipeptidyl nitrile inhibitor, 26)
Affinity DataIC50:  44nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271697(CHEMBL4128244)
Affinity DataIC50:  48nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173311(CHEMBL3810073 | US10023564, Example 6)
Affinity DataIC50:  50nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173325(CHEMBL3809965 | US10023564, Example 5)
Affinity DataIC50:  57nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173314(CHEMBL3808840 | US10023564, Example 16)
Affinity DataIC50:  69nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271696(CHEMBL4125776)
Affinity DataIC50:  77nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271685(CHEMBL4128887)
Affinity DataIC50:  84nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173306(CHEMBL3808565 | US10023564, Example 7)
Affinity DataIC50:  84nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271694(CHEMBL4127007)
Affinity DataIC50:  86nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271693(CHEMBL4126455)
Affinity DataIC50:  92nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271714(CHEMBL4126546)
Affinity DataIC50:  93nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173312(CHEMBL3810312 | US10023564, Example 18)
Affinity DataIC50:  97nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRhodopsin kinase GRK1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173307(CHEMBL3809796 | US10023564, Example 8)
Affinity DataIC50:  100nMAssay Description:Inhibition of GRK1 (unknown origin) using tubulin as substrate by SDS-PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM19861((2S)-N-(cyanomethyl)-4-methyl-2-(phenylformamido)p...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173323(CHEMBL3808621 | US10023564, Example 2)
Affinity DataIC50:  110nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271689(CHEMBL4130028)
Affinity DataIC50:  110nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToxopain-2(Toxoplasma gondii)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271714(CHEMBL4126546)
Affinity DataIC50:  110nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToxopain-2(Toxoplasma gondii)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271696(CHEMBL4125776)
Affinity DataIC50:  120nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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