Compile Data Set for Download or QSAR
maximum 50k data
Found 145 with Last Name = 'klapwijk' and Initial = 'j'
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615811(CHEMBL5272869)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615823(CHEMBL5289520)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615812(CHEMBL5289730)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615791(CHEMBL5275536)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615775(CHEMBL5279860)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615797(CHEMBL5282861)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615779(CHEMBL5285125)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615795(CHEMBL5279371)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615800(CHEMBL5266142)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615813(CHEMBL5269778)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615802(CHEMBL5269001)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615792(CHEMBL5279720)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615825(CHEMBL5266618)
Affinity DataIC50:  5nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615824(CHEMBL5278680)
Affinity DataIC50:  5nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615796(CHEMBL5267588)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615778(CHEMBL5283521)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12983(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615798(CHEMBL5273656)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615782(CHEMBL5282228)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615810(CHEMBL5277213)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615799(CHEMBL5268479)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615808(CHEMBL5289474)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12982(5-Amido-pyrrolopyrazole 9a | CHEMBL385266 | N-{5-[...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615780(CHEMBL5285108)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50526485(CHEMBL4473072)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615809(CHEMBL5288532)
Affinity DataIC50:  10nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615794(CHEMBL5290809)
Affinity DataIC50:  11nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615781(CHEMBL5275367)
Affinity DataIC50:  12nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615776(CHEMBL5278530)
Affinity DataIC50:  12nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615784(CHEMBL5284902)
Affinity DataIC50:  12nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)
Affinity DataIC50:  13nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615804(CHEMBL5283710)
Affinity DataIC50:  13nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615816(CHEMBL5288898)
Affinity DataIC50:  14nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615822(CHEMBL5266974)
Affinity DataIC50:  14nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615777(CHEMBL5271855)
Affinity DataIC50:  14nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615793(CHEMBL5280247)
Affinity DataIC50:  17nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12984(4-(4-methylpiperazin-1-yl)-N-{5-[(2R)-2-phenylprop...)
Affinity DataIC50:  24nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50526529(CHEMBL4483631)
Affinity DataIC50:  25nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12110(1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 18 | 5-N-...)
Affinity DataIC50:  27nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615773(CHEMBL5274762)
Affinity DataIC50:  30nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615788(CHEMBL5272443)
Affinity DataIC50:  31nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615789(CHEMBL5290969)
Affinity DataIC50:  35nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615790(CHEMBL5283878)
Affinity DataIC50:  36nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615785(CHEMBL5274007)
Affinity DataIC50:  37nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615814(CHEMBL5282346)
Affinity DataIC50:  38nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615821(CHEMBL5282999)
Affinity DataIC50:  44nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615771(CHEMBL5276706)
Affinity DataIC50:  45nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12983(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)
Affinity DataIC50:  48nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615783(CHEMBL5284347)
Affinity DataIC50:  56nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12107(1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 15 | 4-(4...)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 145 total ) | Next | Last >>
Jump to: