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Found 2 Enz. Inhib. hit(s) with Target = 'Hematopoietic prostaglandin D synthase' and Ligand = 'BDBM50615821'
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50615821(CHEMBL5282999)
Affinity DataIC50:  44nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHematopoietic prostaglandin D synthase(Rattus norvegicus)TBA
LigandPNGBDBM50615821(CHEMBL5282999)
Affinity DataEC50:  640nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed