Affinity DataKi: 0.00500nMAssay Description:Binding affinity of the compound against Recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Binding affinity of the compound against Recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouseMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from humanMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from humanMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from humanMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from ratMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity of the compound against Recombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity of the compound against Recombinant human thymidylate synthase (TS).More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from hogMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 8.40E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouseMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from hogMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouse liverMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 1.85E+5nMAssay Description:Inhibition of Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 1.88E+5nMAssay Description:Inhibition of Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 3.20E+5nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Tested for inhibition against purified Dihydrofolate reductase from L1210 murine leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair