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Found 39 with Last Name = 'laurent' and Initial = 'c'
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50225551(CHEMBL392378 | N-adamantan-1-ylmethyl-2-chloro-5-(...)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50225550(CHEMBL392558 | N-adamantan-1-ylmethyl-2-chloro-5-p...)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421608(CHEMBL335707)
Affinity DataIC50:  50nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411436(CHEMBL235581)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421607(CHEMBL129975)
Affinity DataIC50:  79nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411442(CHEMBL235579)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421614(CHEMBL131276)
Affinity DataIC50:  126nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421606(CHEMBL337188)
Affinity DataIC50:  158nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421618(CHEMBL130777)
Affinity DataIC50:  158nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421610(CHEMBL337413)
Affinity DataIC50:  158nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421611(CHEMBL422433)
Affinity DataIC50:  158nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421612(CHEMBL128514)
Affinity DataIC50:  158nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421616(CHEMBL335058)
Affinity DataIC50:  200nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421609(CHEMBL131105)
Affinity DataIC50:  200nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411437(CHEMBL392559)
Affinity DataIC50:  251nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411443(CHEMBL235357)
Affinity DataIC50:  316nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411435(CHEMBL236860)
Affinity DataIC50:  316nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411444(CHEMBL393348)
Affinity DataIC50:  316nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411429(CHEMBL235789)
Affinity DataIC50:  398nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411439(CHEMBL235580)
Affinity DataIC50:  501nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411428(CHEMBL393384)
Affinity DataIC50:  631nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421615(CHEMBL132173)
Affinity DataIC50:  631nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421617(CHEMBL336571)
Affinity DataIC50:  631nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411441(CHEMBL393821)
Affinity DataIC50:  794nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411430(CHEMBL235791)
Affinity DataIC50:  794nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50411431(CHEMBL393717)
Affinity DataIC50:  1.26E+3nMAssay Description:Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414327(CHEMBL128537)
Affinity DataIC50:  6.31E+3nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50225552(CHEMBL235393 | N-adamantan-1-ylmethyl-2-methyl-5-(...)
Affinity DataIC50:  7.00E+3nMAssay Description:Activity at vasopressin V1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50225553(CHEMBL393754 | N-adamantan-1-ylmethyl-2-chloro-5-(...)
Affinity DataIC50:  7.00E+3nMAssay Description:Activity at vasopressin V1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222402(CHEMBL424070)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421613(CHEMBL128481)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222401(CHEMBL338652)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222400(CHEMBL130520)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222404(CHEMBL129876)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222398(CHEMBL128518)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222399(CHEMBL337016)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222403(CHEMBL131381)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222405(CHEMBL130571)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222397(CHEMBL131434)
Affinity DataIC50: <1.00E+4nMAssay Description:In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed