Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 insect cells assessed as inhibition of poly(Glu,Tyr) 4:1 substrate phosphorylation by radiome...More data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 insect cells assessed as inhibition of poly(Glu,Tyr) 4:1 substrate phosphorylation by radiome...More data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair