Compile Data Set for Download or QSAR
maximum 50k data
Found 54 with Last Name = 'liekens' and Initial = 's'
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50403106(CHEMBL2216916)
Affinity DataKi:  18nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50403105(CHEMBL2216917)
Affinity DataKi:  178nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50:  20nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50:  60nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  63nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  71nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50:  220nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(CHEMBL1762225 | exo-(S)-5-fluoro-4-hydroxy-1-(3-me...)
Affinity DataIC50:  430nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(CHEMBL1762230 | exo-1-((2S,4S,5R)-4,5-dihydroxy-3-...)
Affinity DataIC50:  570nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50:  600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  830nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  950nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(CHEMBL1762225 | exo-(S)-5-fluoro-4-hydroxy-1-(3-me...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194179(1-(cyclopropyl)methyl-5'-O-tritylinosine | CHEMBL3...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(CHEMBL1762230 | exo-1-((2S,4S,5R)-4,5-dihydroxy-3-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194181(1-(cyclohexyl)methyl-5'-O-tritylinosine | CHEMBL21...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194173(5'-O-[(4-chlorophenyl)-1,1-(diphenyl)methyl]inosin...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(CHEMBL1762230 | exo-1-((2S,4S,5R)-4,5-dihydroxy-3-...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(CHEMBL1762230 | exo-1-((2S,4S,5R)-4,5-dihydroxy-3-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(CHEMBL1762230 | exo-1-((2S,4S,5R)-4,5-dihydroxy-3-...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(CHEMBL1762225 | exo-(S)-5-fluoro-4-hydroxy-1-(3-me...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(CHEMBL1762225 | exo-(S)-5-fluoro-4-hydroxy-1-(3-me...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(CHEMBL1762225 | exo-(S)-5-fluoro-4-hydroxy-1-(3-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(CHEMBL1762225 | exo-(S)-5-fluoro-4-hydroxy-1-(3-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194174(1-benzyl-5'-O-tritylinosine | CHEMBL441540)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194175(1-allyl-5'-O-tritylinosine | CHEMBL213891)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194170(1-propyl-5'-O-tritylinosine | CHEMBL213890)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194176(5-amino-1-(5-O-trityl-beta-D-ribofuranosyl)imidazo...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194168(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)m...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194184(5-amino-1-(5-O-trityl-beta-D-ribofuranosyl)imidazo...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194186(2',3'-Di-O-acetyl-5'-O-trityl-1-[(2-methoxyethoxy)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50365128(CHEMBL1949835 | CHEMBL2216906)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 insect cells assessed as inhibition of poly(Glu,Tyr) 4:1 substrate phosphorylation by radiome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194185(5-amino-1-(5-O-trityl-beta-D-ribofuranosyl)imidazo...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194180(1-[(E)-3-methoxycarbonyl-2-propenyl]-5'-O-tritylin...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194178(6-chloro-9-(5-O-trityl-beta-D-ribofuranosyl)purine...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194172(5'-O-tritylinosine | CHEMBL386148)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194189(9-(5-O-trityl-beta-D-ribofuranosyl)purine | CHEMBL...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194177(1-methyl-5'-O-tritylinosine | CHEMBL212853)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194187(5-amino-1-(5-O-trityl-beta-D-ribofuranosyl)imidazo...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50349611(CHEMBL1808951 | CHEMBL2216905)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 insect cells assessed as inhibition of poly(Glu,Tyr) 4:1 substrate phosphorylation by radiome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50194188(5'-O-trityl-2'deoxyinosine | CHEMBL209655)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of human TPase in presence of 100 uM thymidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 54 total ) | Next | Last >>
Jump to: