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Found 50 with Last Name = 'lugari' and Initial = 'a'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326574(6-phenylpyridazin-3-yl thiophene-2-carboxylate | C...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326574(6-phenylpyridazin-3-yl thiophene-2-carboxylate | C...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM33627((1,3-benzoxazol-2-ylthio)formic acid butyl ester |...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM33627((1,3-benzoxazol-2-ylthio)formic acid butyl ester |...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326573(1-Phenyl-3-(2-thiazolyl)-2-thiourea | 1-phenyl-3-(...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326573(1-Phenyl-3-(2-thiazolyl)-2-thiourea | 1-phenyl-3-(...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM47541(1-(2-chlorophenyl)-3-(2-pyridinyl)thiourea | 1-(2-...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM47541(1-(2-chlorophenyl)-3-(2-pyridinyl)thiourea | 1-(2-...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of GST-tagged human BRD2 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human BRD3 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326572(CHEMBL1253383 | N-(2-bromobenzoyloxy)-4-chlorobenz...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326572(CHEMBL1253383 | N-(2-bromobenzoyloxy)-4-chlorobenz...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150755(CHEMBL3775270)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150755(CHEMBL3775270)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human BRD3 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150755(CHEMBL3775270)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of GST-tagged human BRD2 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326570((1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)m...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150755(CHEMBL3775270)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150755(CHEMBL3775270)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326571(5-(2-nitro-4-(trifluoromethylsulfonyl)phenylthio)-...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326570((1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)m...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150755(CHEMBL3775270)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326569(CHEMBL1253492 | methyl 2-(4-methyl-5-(thiophen-2-y...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150755(CHEMBL3775270)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150753(CHEMBL3775772)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150752(CHEMBL3774900)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326569(CHEMBL1253492 | methyl 2-(4-methyl-5-(thiophen-2-y...)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150752(CHEMBL3774900)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150752(CHEMBL3774900)
Affinity DataIC50:  3.17E+4nMAssay Description:Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50096008(3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...)
Affinity DataIC50:  4.52E+4nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150714(CHEMBL3775080)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326576(3-(2,4-difluorophenylamino)-1-(5-methylfuran-2-yl)...)
Affinity DataIC50:  5.75E+4nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326568(CHEMBL1253493 | N-(furan-2-ylmethyl)-7-nitrobenzo[...)
Affinity DataIC50:  6.04E+4nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326567(CHEMBL1253544 | ethyl 2-cyano-3-(2,4-dihydroxyphen...)
Affinity DataIC50:  6.21E+4nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM52230((Z)-2-(1,3-benzoxazol-2-yl)-3-(2-pyridinylamino)-2...)
Affinity DataIC50:  6.42E+4nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150752(CHEMBL3774900)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human ATAD2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50096008(3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326567(CHEMBL1253544 | ethyl 2-cyano-3-(2,4-dihydroxyphen...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute

Curated by ChEMBL
LigandPNGBDBM50326577(3-nitroso-2-phenylindolizine | CHEMBL1253586)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to his-tagged human BRD4 bromodomain1 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150754(CHEMBL3775058)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to his-tagged human BRD4 bromodomain1 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair