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Found 103 with Last Name = 'lundeen' and Initial = 'sg'
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  0.0540nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222089((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-et...)
Affinity DataIC50:  0.340nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222091((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15...)
Affinity DataIC50:  0.590nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222086((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  0.630nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222092((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  0.980nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222088((3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-m...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50201772(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-1,1,1-tr...)
Affinity DataIC50:  2nMAssay Description:Binding affinity at androgen receptor expressed in COS cells by whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222087((3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyph...)
Affinity DataIC50:  4.60nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50201773(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-1,1,1-tr...)
Affinity DataIC50:  7nMAssay Description:Binding affinity at androgen receptor expressed in COS cells by whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50201771(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3-(ethyl...)
Affinity DataIC50:  17nMAssay Description:Binding affinity at androgen receptor expressed in COS cells by whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222085((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222092((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185197(11-methyl-6,11-dihydro-5H-pyrido[3,2-a]carbazol-8-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185206(11-methyl-6,11-dihydro-5H-benzo[a]carbazol-9-ol | ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185194(11-methyl-6,11-dihydro-5-thia-4,11-diaza-benzo[a]f...)
Affinity DataIC50:  52nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222090((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222086((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185207(2-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185210(11-methyl-6,11-dihydrothiochromeno[4,3-b]indol-8-o...)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185191(11-methyl-6,11-dihydrothiochromeno[4,3-b]indol-9-o...)
Affinity DataIC50:  130nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222089((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-et...)
Affinity DataIC50:  210nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185202(3,10-dimethyl-3,4,5,10-tetrahydropyrrolo[3,2-a]car...)
Affinity DataIC50:  370nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222091((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15...)
Affinity DataIC50:  460nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222085((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...)
Affinity DataIC50:  540nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185190(10-methyl-5,10-dihydro-4H-thieno[3,2-a]carbazol-7-...)
Affinity DataIC50:  580nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185209(3-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50:  630nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222087((3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyph...)
Affinity DataIC50:  660nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)
Affinity DataIC50:  850nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185201(11-methyl-6,11-dihydrothiochromeno[4,3-b]indol-8-y...)
Affinity DataIC50:  880nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185213(12-methyl-5,6,7,12-tetrahydro-benzo[6,7]cyclohepta...)
Affinity DataIC50:  920nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185199(11-methyl-6,11-dihydro-5H-pyrido[4,3-a]carbazol-8-...)
Affinity DataIC50:  930nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185212(1-(8-hydroxythiochromeno[4,3-b]indol-11(6H)-yl)eth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185193(8-chloro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185211(11-methyl-6,11-dihydrothiochromeno[4,3-b]indole-3,...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185192(11-ethyl-6,11-dihydrothiochromeno[4,3-b]indol-8-ol...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185208(3-bromo-11-methyl-6,11-dihydrothiochromeno[4,3-b]i...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185204(8-fluoro-11-methyl-3-(trifluoromethyl)-6,11-dihydr...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185195(3-methoxy-11-methyl-6,11-dihydrothiochromeno[4,3-b...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185198(6,6,11-trimethyl-6,11-dihydrothiochromeno[4,3-b]in...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185205(8-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185200(3-fluoro-11-methyl-6,11-dihydrothiochromeno[4,3-b]...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185203(6,11-dihydrothiochromeno[4,3-b]indol-8-ol | CHEMBL...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50185189(12-methyl-6,7-dihydro-12H-5-thia-12-aza-dibenzo[a,...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat AR-mediated reporter gene expression in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222088((3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50222090((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50010132((3S,4R)-3-Hydroxy-2,2-dimethyl-4-(2-oxo-pyrrolidin...)
Affinity DataEC50:  1.25E+3nMAssay Description:Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPRMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50240750(()-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylprop...)
Affinity DataEC50:  3.54E+3nMAssay Description:Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50062397(3N-cyanoimino(tert-pentylamino)methyl-3-pyridinami...)
Affinity DataEC50:  230nMAssay Description:Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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