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Found 144 with Last Name = 'makawana' and Initial = 'ja'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50029085(CHEBI:83405 | CHEMBL525191 | GDC-0879)
Affinity DataKi:  0.130nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  32nMAssay Description:Inhibition of autophosphorylation of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by DELFIA/t...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation expressed in baculovirus infected insect Sf9 cel...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  32nMAssay Description:Inhibition of autophosphorylation of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by time-res...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50103527(CHEMBL3325477)
Affinity DataIC50:  90nMAssay Description:Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009639(CHEMBL3235202)
Affinity DataIC50:  120nMAssay Description:Inhibition of autophosphorylation of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by time-res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  160nMAssay Description:Inhibition of autophosphorylation of human HER2 cytoplasmic domain (amino acids 676 to 1245) (unknown origin) expressed in Sf9 cells after 1 hr by ti...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009638(CHEMBL3235201)
Affinity DataIC50:  180nMAssay Description:Inhibition of autophosphorylation of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by time-res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50103527(CHEMBL3325477)
Affinity DataIC50:  200nMAssay Description:Inhibition of histidine-tagged recombinant HER2 (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphorylation by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50102489(CHEMBL3325479)
Affinity DataIC50:  200nMAssay Description:Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of histidine-tagged recombinant HER2 (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphorylation by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50443294(CHEMBL3088220)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation expressed in baculovirus infected insect Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009642(CHEMBL3234866)
Affinity DataIC50:  270nMAssay Description:Inhibition of autophosphorylation of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by time-res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009643(CHEMBL3234867)
Affinity DataIC50:  370nMAssay Description:Inhibition of autophosphorylation of human HER2 cytoplasmic domain (amino acids 676 to 1245) (unknown origin) expressed in Sf9 cells after 1 hr by ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009640(CHEMBL3235203)
Affinity DataIC50:  420nMAssay Description:Inhibition of autophosphorylation of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by time-res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50443293(CHEMBL3088219)
Affinity DataIC50:  430nMAssay Description:Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation expressed in baculovirus infected insect Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009640(CHEMBL3235203)
Affinity DataIC50:  430nMAssay Description:Inhibition of autophosphorylation of human HER2 cytoplasmic domain (amino acids 676 to 1245) (unknown origin) expressed in Sf9 cells after 1 hr by ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50016095(CHEMBL3261192)
Affinity DataIC50:  450nMAssay Description:Inhibition of FAK (unknown origin) assembly after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  500nMAssay Description:Inhibition of FAK (unknown origin) assembly after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009023(CHEMBL3237948)
Affinity DataIC50:  510nMAssay Description:Inhibition of autophosphorylation of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by DELFIA/t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50102489(CHEMBL3325479)
Affinity DataIC50:  800nMAssay Description:Inhibition of histidine-tagged recombinant HER2 (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphorylation by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009020(CHEMBL3237945)
Affinity DataIC50:  910nMAssay Description:Inhibition of autophosphorylation of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by DELFIA/t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50016096(CHEMBL3261193)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009024(CHEMBL3237949)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of autophosphorylation of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by DELFIA/t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50103531(CHEMBL3325473)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50103528(CHEMBL3325475)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009637(CHEMBL3235200)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of autophosphorylation of human HER2 cytoplasmic domain (amino acids 676 to 1245) (unknown origin) expressed in Sf9 cells after 1 hr by ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50045307(CHEMBL3311089)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50016084(CHEMBL3261182)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of bovine brain tubulin preincubated for 20 mins by turbidimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50443295(CHEMBL3088221)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation expressed in baculovirus infected insect Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50103531(CHEMBL3325473)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of histidine-tagged recombinant HER2 (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphorylation by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009018(CHEMBL3237944)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of autophosphorylation of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by DELFIA/t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50103528(CHEMBL3325475)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of histidine-tagged recombinant HER2 (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphorylation by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009639(CHEMBL3235202)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of autophosphorylation of human HER2 cytoplasmic domain (amino acids 676 to 1245) (unknown origin) expressed in Sf9 cells after 1 hr by ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50056757(CHEMBL3331011)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of bovine brain tubulin preincubated for 20 mins by turbidimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50443296(CHEMBL3088222)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) autophosphorylation expressed in baculovirus infected insect Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50045305(CHEMBL3311087)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009637(CHEMBL3235200)
Affinity DataIC50:  3.17E+3nMAssay Description:Inhibition of autophosphorylation of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by time-res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50016080(CHEMBL3261178)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50102490(CHEMBL3325478)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of histidine-tagged recombinant HER2 (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphorylation by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009644(CHEMBL3235199)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of autophosphorylation of human HER2 cytoplasmic domain (amino acids 676 to 1245) (unknown origin) expressed in Sf9 cells after 1 hr by ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50008995(CHEMBL3237940)
Affinity DataIC50:  4.15E+3nMAssay Description:Inhibition of autophosphorylation of recombinant EGFR cytoplasmic domain (645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by DELFIA/t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50103532(CHEMBL3325474)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50016085(CHEMBL3261183)
Affinity DataIC50:  4.34E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50102485(CHEMBL3327179)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
School Of Life Science Nanjing University

Curated by ChEMBL
LigandPNGBDBM50031298(CHEMBL3352863)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of Escherichia coli FabHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50009644(CHEMBL3235199)
Affinity DataIC50:  5.12E+3nMAssay Description:Inhibition of autophosphorylation of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells after 1 hr by time-res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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