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Found 235 with Last Name = 'martinez' and Initial = 'y'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171394(2-Decyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | CH...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171396(1-((R)-4-Amino-pyrazolo[3,4-d]pyrimidin-2-yl)-deca...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50213599((6aR,10aR)-3-(6-bromo-2-methylhexan-2-yl)-6,6,9-tr...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171395(2-Undecyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | ...)
Affinity DataKi:  0.470nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337798((6aR,10aR)-3-(8-bromo-2-methyloctan-2-yl)-6,6,9-tr...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171393(2-Nonyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | CH...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337797((6aR,10aR)-3-(5-bromopentyl)-6,6,9-trimethyl-6a,7,...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50402202(CHEMBL2203964)
Affinity DataKi:  11nMAssay Description:Inhibition of human GLO1More data for this Ligand-Target Pair
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50092825(CHEMBL128935 | S-(N-phenyl-N-hydroxycarbamoyl)glut...)
Affinity DataKi:  14nMAssay Description:Inhibition of human GLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337796((6aR,10aR)-3-(4-bromobutyl)-6,6,9-trimethyl-6a,7,1...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337799((6aR,10aR)-6,6,9-trimethyl-3-(5,5,5-trifluoropenty...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337803(3-(4-amino-2H-pyrazolo[3,4-d]pyrimidin-2-yl)nonan-...)
Affinity DataKi:  53nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337800((6aR,10aR)-9-(fluoromethyl)-6,6-dimethyl-3-pentyl-...)
Affinity DataKi:  103nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517464(CHEMBL1234300)
Affinity DataKi:  230nMAssay Description:Inhibition of human GLO1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337795((6aR,10aR)-6,6,9-trimethyl-3-(octan-2-yl)-6a,7,10,...)
Affinity DataKi:  328nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171387(2-Octyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | CH...)
Affinity DataKi:  530nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171391(2-Heptyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | C...)
Affinity DataKi:  818nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337801(2-Hexyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | 2-...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337802(2-Dodecyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | ...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337804(5-(7-(benzyloxy)quinazolin-4-ylamino)-4-fluoro-2-m...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption by ELISA assay in presence of 20 uM ATPChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM5432(6-(4-methoxyphenyl)-3-(thiophen-3-yl)pyrazolo[1,5-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption by ELISA assay in presence of 20 uM ATPChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222276(6,7-dihydroxy-4'-methoxyisoflavan | CHEMBL239247)
Affinity DataIC50:  150nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222277(6,7-dihydroxy-3'-methylisoflavan | CHEMBL239893)
Affinity DataIC50:  210nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222295(6,7-dihydroxy-3-m-tolyl-2,3-dihydrochromen-4-one |...)
Affinity DataIC50:  210nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  250nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222307(6,7-dihydroxy-3',4'-methylenedioxyisoflavan | CHEM...)
Affinity DataIC50:  350nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517468(CHEMBL4559294)
Affinity DataIC50:  370nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  440nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517488(CHEMBL4516514)
Affinity DataIC50:  460nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517469(CHEMBL4543065)
Affinity DataIC50:  480nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222293(4'-chloro-7,8-dihydroxyisoflavone | CHEMBL241814)
Affinity DataIC50:  480nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517474(CHEMBL4539074)
Affinity DataIC50:  500nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50139862(3-(4-Hydroxy-phenyl)-chroman-6,7-diol | 4',6,7-tri...)
Affinity DataIC50:  510nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517465(CHEMBL4457949)
Affinity DataIC50:  540nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517466(CHEMBL4571524)
Affinity DataIC50:  590nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222308(7,8-dihydroxy-30-trifluoromethylisoflavone | CHEMB...)
Affinity DataIC50:  620nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517473(CHEMBL4573731)
Affinity DataIC50:  640nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517471(CHEMBL4466017)
Affinity DataIC50:  720nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222290(3'-chloro-7,8-dihydroxyisoflavone | CHEMBL241815 |...)
Affinity DataIC50:  780nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517463(CHEMBL4532036)
Affinity DataIC50:  790nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517437(CHEMBL4514413)
Affinity DataIC50:  790nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM4620(Anilinoquinazoline deriv. 3 | N-(4-chlorophenyl)-6...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption by ELISA assay in presence of 20 uM ATPChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  860nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  950nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517467(CHEMBL4580349)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517461(CHEMBL4575972)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517462(CHEMBL4467660)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517483(CHEMBL3981698)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoylglutathione lyase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517489(CHEMBL4454726)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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