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Found 57 with Last Name = 'mccall' and Initial = 'o'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26707(7-chloro-9-ethyl-6-hydroxy-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  2.5nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26698(7-chloro-6-fluoro-9-(propan-2-yl)-1H,3H,4H,9H-quin...)
Affinity DataKi:  12.3nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26699(9-butyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26697(7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  21.8nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26700(9-benzyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  36.5nM ΔG°:  -42.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26707(7-chloro-9-ethyl-6-hydroxy-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  43.5nM ΔG°:  -41.6kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26701(7-chloro-9-ethyl-6-fluoro-1-methyl-1H,3H,4H,9H-qui...)
Affinity DataKi:  50.1nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26698(7-chloro-6-fluoro-9-(propan-2-yl)-1H,3H,4H,9H-quin...)
Affinity DataKi:  62.8nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26699(9-butyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  165nM ΔG°:  -38.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26697(7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  174nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26703(7-chloro-9-ethyl-6-fluoro-1-[(3-hydroxyphenyl)meth...)
Affinity DataKi:  271nM ΔG°:  -37.1kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26700(9-benzyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  558nM ΔG°:  -35.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26705(7-chloro-9-ethyl-6-fluoro-1-(2-hydroxyethyl)-1H,3H...)
Affinity DataKi:  1.16E+3nM ΔG°:  -33.5kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26702(1-benzyl-7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-qui...)
Affinity DataKi:  1.27E+3nM ΔG°:  -33.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26701(7-chloro-9-ethyl-6-fluoro-1-methyl-1H,3H,4H,9H-qui...)
Affinity DataKi: >1.42E+3nM ΔG°: >-33.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26706(7-chloro-9-ethyl-6-methoxy-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi: >1.42E+3nM ΔG°: >-33.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26702(1-benzyl-7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-qui...)
Affinity DataKi: >1.42E+3nM ΔG°: >-33.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26703(7-chloro-9-ethyl-6-fluoro-1-[(3-hydroxyphenyl)meth...)
Affinity DataKi: >1.42E+3nM ΔG°: >-33.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26704(1-[2-(benzyloxy)ethyl]-7-chloro-9-ethyl-6-fluoro-1...)
Affinity DataKi: >1.42E+3nM ΔG°: >-33.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26705(7-chloro-9-ethyl-6-fluoro-1-(2-hydroxyethyl)-1H,3H...)
Affinity DataKi: >1.42E+3nM ΔG°: >-33.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26706(7-chloro-9-ethyl-6-methoxy-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  2.70E+3nM ΔG°:  -31.5kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26704(1-[2-(benzyloxy)ethyl]-7-chloro-9-ethyl-6-fluoro-1...)
Affinity DataKi:  4.89E+3nM ΔG°:  -30.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137758(2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...)
Affinity DataIC50:  22nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137762(2-Chloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6,7-t...)
Affinity DataIC50:  54nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137786(2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...)
Affinity DataIC50:  67nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137768(2,4-Dichloro-N-(3-cyano-6-phenyl-4,5,6,7-tetrahydr...)
Affinity DataIC50:  70nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137760(2,4-dichloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[...)
Affinity DataIC50:  300nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137775(2,4-DICHLORO-N-(3-CYANO-4,5,6,7-TETRAHYDRO-BENZOTH...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137759(2-chloro-N-(3-cyano-4,5,6,7-tetrahydro-benzo[b]thi...)
Affinity DataIC50:  1.40E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137752(2-Chloro-N-(3-cyano-4,5,6,7-tetrahydro-benzo[b]thi...)
Affinity DataIC50:  1.70E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137761(2-chloro-N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohep...)
Affinity DataIC50:  3.40E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137783(2-Chloro-N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohep...)
Affinity DataIC50:  4.20E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137756(2-Bromo-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thi...)
Affinity DataIC50:  4.20E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137780(2,4-dichloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[...)
Affinity DataIC50:  5.20E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137769(2-(2-Chloro-5-diethylsulfamoyl-benzoylamino)-3-cya...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137779(2-chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50:  6.40E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137781(2-chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50:  8.00E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137778(2-Chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50:  8.00E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137757(2-Chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50:  9.00E+3nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137766(2-chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50:  1.50E+4nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137770(2-chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50:  2.60E+4nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137767(2-Chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50:  6.20E+4nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137782(2-(2-chloro-5-diethylsulfamoyl-benzoylamino)-5,6-d...)
Affinity DataIC50:  6.60E+4nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137764(CHEMBL431263 | N-(3-cyano-5,6-dihydro-4H-cyclopent...)
Affinity DataIC50:  7.40E+4nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137785(2-chloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]th...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137784(4-Chloro-3-[(3-cyano-5,6-dihydro-4H-cyclopenta[b]t...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137776(CHEMBL91833 | N-(3-Cyano-5,6-dihydro-4H-cyclopenta...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137774(CHEMBL313359 | N-(3-Aminomethyl-5,6-dihydro-4H-cyc...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137772(CHEMBL91823 | N-(3-Cyano-5,6-dihydro-4H-cyclopenta...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137777(CHEMBL89936 | N-(3-cyano-5,6-dihydro-4H-cyclopenta...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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