Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM26697'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26697(7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  21.8nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26697(7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  22nMAssay Description:Inhibition of Pim1 (unknown origin) assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotomet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed