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Found 1204 with Last Name = 'medina' and Initial = 'm'
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataKi:  0.460nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533717(CHEMBL4449284)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  0.75nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50528969(CHEMBL4458337)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50528969(CHEMBL4458337)
Affinity DataKi:  0.910nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533719(CHEMBL4441457)
Affinity DataKi:  0.940nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533718(CHEMBL4530421)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533719(CHEMBL4441457)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533717(CHEMBL4449284)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533720(CHEMBL4557905)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataKi:  2.90nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533718(CHEMBL4530421)
Affinity DataKi:  6.10nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataKi:  19nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533720(CHEMBL4557905)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533720(CHEMBL4557905)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  37nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533719(CHEMBL4441457)
Affinity DataKi:  39nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533717(CHEMBL4449284)
Affinity DataKi:  47nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50528969(CHEMBL4458337)
Affinity DataKi:  51nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  90nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  131nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533722(CHEMBL4476666)
Affinity DataKi:  136nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533718(CHEMBL4530421)
Affinity DataKi:  170nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataKi:  230nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataKi:  231nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533722(CHEMBL4476666)
Affinity DataKi:  249nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533722(CHEMBL4476666)
Affinity DataKi:  258nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533721(CHEMBL4459868)
Affinity DataKi:  375nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533721(CHEMBL4459868)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533721(CHEMBL4459868)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50079527((3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimet...)
Affinity DataIC50:  0.00300nMAssay Description:Compound tested for its inhibitory activity against Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataIC50:  0.00600nMAssay Description:Compound tested for its inhibitory activity against Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Landsteiner Genmed

US Patent
LigandPNGBDBM535882(US11242312, Example 3)
Affinity DataIC50:  0.00800nMAssay Description:Activity of Calpain 1 was measured by using Calpain-Glo Protease kit from Promega. Assays were run in 384-well black plates with clear bottom. 5 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50079527((3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimet...)
Affinity DataIC50:  0.0100nMAssay Description:Compound was tested for its inhibitory activity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataIC50:  0.0200nMAssay Description:Compound was tested for its inhibitory activity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9022(CHEMBL225567 | Indole-Tacrine Heterodimer 5 | N-[5...)
Affinity DataIC50:  0.0200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataIC50:  0.0200nMAssay Description:Compound tested for its inhibitory activity against Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9027(3-(1H-indol-3-yl)-N-(3-{methyl[3-(1,2,3,4-tetrahyd...)
Affinity DataIC50:  0.0300nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Landsteiner Genmed

US Patent
LigandPNGBDBM535880(US11242312, Example 1)
Affinity DataIC50:  0.0300nMAssay Description:Activity of Calpain 1 was measured by using Calpain-Glo Protease kit from Promega. Assays were run in 384-well black plates with clear bottom. 5 _...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)
Affinity DataIC50:  0.0400nMAssay Description:Compound was tested for its inhibitory activity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM77970(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)
Affinity DataIC50:  0.0400nMAssay Description:Compound was tested for its inhibitory activity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)
Affinity DataIC50:  0.0500nMAssay Description:Compound tested for its inhibitory activity against Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9023(CHEMBL225198 | Indole-Tacrine Heterodimer 6 | N-[7...)
Affinity DataIC50:  0.0600nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Affinity DataIC50:  0.0600nMAssay Description:Compound tested for its inhibitory activity against Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataIC50:  0.0700nMAssay Description:Compound was tested for its inhibitory activity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9023(CHEMBL225198 | Indole-Tacrine Heterodimer 6 | N-[7...)
Affinity DataIC50:  0.100nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9035(Indole-Tacrine Heterodimer 18 | N-[7-(6-Chloro-1,2...)
Affinity DataIC50:  0.200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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