Found 9 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50474152' TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 123nMAssay Description:Inhibition of kappa opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Displacement of [3H]U69,593 from human recombinant kappa opioid receptor expressed in rat RBL cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Affinity DataKi: 231nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 772nMAssay Description:Binding affinity to KOP (unknown origin)More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]U-69593 from kappa opoid receptor in Dunkin-Hartley guinea pig brain after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor kappa 1 using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: >4.00E+3nMAssay Description:Antagonist activity at mouse kappa opioid receptor-1 expressed in CHO cell membranes assessed as inhibition of U50,488H-induced [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+3nMAssay Description:Agonist activity at KOP (unknown origin)More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania
Curated by ChEMBL
University Of Catania
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
