Affinity DataKi: 2.20nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1/REST corepressor 3(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of HDAC1/CoREST3 in HEK293 whole cell extract using fluorescent acetylated histone peptide as substrate after 60 mins by fluorescence base...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Irreversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1/REST corepressor 3(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibition of HDAC1/CoREST3 in HEK293 whole cell extract using fluorescent acetylated histone peptide as substrate after 60 mins by fluorescence base...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/REST corepressor 3(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of HDAC1/CoREST3 in HEK293 whole cell extract using fluorescent acetylated histone peptide as substrate after 60 mins by fluorescence base...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Irreversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated f...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 4.90E+3nMAssay Description:Competitive inhibition of MAOA in human SH-SY5Y cells using p-tyramine as substrate preincubated for 5 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Irreversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated f...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Competitive inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot a...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.30E+4nMAssay Description:Mixed type inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:Mixed type inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.29E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.70E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.86E+5nMAssay Description:Reversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.88E+5nMAssay Description:Reversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.26E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.91E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 4.14E+5nMAssay Description:Reversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 7.85E+5nMAssay Description:Reversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 9.97E+5nMAssay Description:Reversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.05E+6nMAssay Description:Reversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.253nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.471nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Chiba University
Curated by ChEMBL
Chiba University
Curated by ChEMBL
Affinity DataIC50: 0.950nMAssay Description:Antagonist activity at recombinant GluN1/GluN2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glycine/gluta...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.66nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.32nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Chiba University
Curated by ChEMBL
Chiba University
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at recombinant GluN1/GluN2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glycine/gluta...More data for this Ligand-Target Pair
Affinity DataIC50: 4.83nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10.8nMAssay Description:Inhibition of human serum recombinant BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Chiba University
Curated by ChEMBL
Chiba University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at recombinant GluN1/GluN2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glycine/gluta...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12.1nMAssay Description:Inhibition of human serum recombinant BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Inhibition of human serum recombinant BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15.9nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16.1nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair