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Found 127 with Last Name = 'nolen' and Initial = 'hw'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020515(2-(Hydroxyimino-methyl)-3-methyl-1-(naphthalen-1-y...)
Affinity DataKi:  3.50E+3nMAssay Description:Compound was tested for the competitive inhibition of phosphorylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020529(2-(Hydroxyimino-methyl)-3-methyl-1-(3-phenyl-propo...)
Affinity DataKi:  4.00E+3nMAssay Description:Compound was tested for the competitive inhibition of phosphonylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020521(2-(Hydroxyimino-methyl)-3-methyl-1-(1,2,2-trimethy...)
Affinity DataKi:  7.60E+3nMAssay Description:Compound was tested for the competitive inhibition of phosphonylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020514(2-(Hydroxyimino-methyl)-1-methoxymethyl-3-methyl-3...)
Affinity DataKi:  4.80E+4nMAssay Description:Compound was tested for the competitive inhibition of phosphorylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50011780(2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium ch...)
Affinity DataKi:  1.27E+5nMAssay Description:Compound was tested for the competitive inhibition of phosphorylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020522(1-(((4-carbamoylpyridinium-1-yl)methoxy)methyl)-2-...)
Affinity DataKi:  2.29E+5nMAssay Description:Compound was tested for the competitive inhibition of phosphonylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025238(CHEMBL71740 | N-Hydroxy-3-octyl-[1,2,4]oxadiazole-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was tested for the concentration required for reversible inhibition of human acetylcholinesterase .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50025251(CHEMBL302946 | N-Hydroxy-3-naphthalen-1-yl-[1,2,4]...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro reversible inhibition of eel acetylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50025238(CHEMBL71740 | N-Hydroxy-3-octyl-[1,2,4]oxadiazole-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was tested for the concentration required for reversible inhibition of eel acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020516(2-(3-{2-[2-hydroxy-(E)-1-methenylimino]-1-methyl-1...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020515(2-(Hydroxyimino-methyl)-3-methyl-1-(naphthalen-1-y...)
Affinity DataIC50:  3.80E+3nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020515(2-(Hydroxyimino-methyl)-3-methyl-1-(naphthalen-1-y...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025242(CHEMBL20339 | CHEMBL2079594 | N-Hydroxy-3-phenyl-[...)
Affinity DataIC50:  6.00E+3nMAssay Description:Reactivation of human acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020515(2-(Hydroxyimino-methyl)-3-methyl-1-(naphthalen-1-y...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020517(2-(Hydroxyimino-methyl)-3-methyl-1-octyloxymethyl-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine O-acetyltransferase(RAT)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020515(2-(Hydroxyimino-methyl)-3-methyl-1-(naphthalen-1-y...)
Affinity DataIC50:  7.00E+3nMAssay Description:Compound was tested for the competitive inhibition of acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50025242(CHEMBL20339 | CHEMBL2079594 | N-Hydroxy-3-phenyl-[...)
Affinity DataIC50:  7.50E+3nMAssay Description:In vitro reversible inhibition of eel acetylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020516(2-(3-{2-[2-hydroxy-(E)-1-methenylimino]-1-methyl-1...)
Affinity DataIC50:  7.80E+3nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020519(1-(2,2-Dimethyl-propoxymethyl)-2-(hydroxyimino-met...)
Affinity DataIC50:  8.40E+3nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020519(1-(2,2-Dimethyl-propoxymethyl)-2-(hydroxyimino-met...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020517(2-(Hydroxyimino-methyl)-3-methyl-1-octyloxymethyl-...)
Affinity DataIC50:  9.50E+3nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020517(2-(Hydroxyimino-methyl)-3-methyl-1-octyloxymethyl-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020521(2-(Hydroxyimino-methyl)-3-methyl-1-(1,2,2-trimethy...)
Affinity DataIC50:  1.15E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50367852(CHEMBL538352)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020519(1-(2,2-Dimethyl-propoxymethyl)-2-(hydroxyimino-met...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine O-acetyltransferase(RAT)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020529(2-(Hydroxyimino-methyl)-3-methyl-1-(3-phenyl-propo...)
Affinity DataIC50:  1.50E+4nMAssay Description:Compound was tested for the competitive inhibition of acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020529(2-(Hydroxyimino-methyl)-3-methyl-1-(3-phenyl-propo...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020521(2-(Hydroxyimino-methyl)-3-methyl-1-(1,2,2-trimethy...)
Affinity DataIC50:  1.60E+4nMAssay Description:Compound was tested for the competitive inhibition of phosphonylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine O-acetyltransferase(RAT)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020521(2-(Hydroxyimino-methyl)-3-methyl-1-(1,2,2-trimethy...)
Affinity DataIC50:  1.60E+4nMAssay Description:Compound was tested for the competitive inhibition of acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020521(2-(Hydroxyimino-methyl)-3-methyl-1-(1,2,2-trimethy...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020518(1-Butoxymethyl-2-(hydroxyimino-methyl)-3-methyl-3H...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020529(2-(Hydroxyimino-methyl)-3-methyl-1-(3-phenyl-propo...)
Affinity DataIC50:  2.12E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Mus musculus)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020529(2-(Hydroxyimino-methyl)-3-methyl-1-(3-phenyl-propo...)
Affinity DataIC50:  2.20E+4nMAssay Description:Compound was tested for the binding affinity towards muscarinic receptor in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020534(1-(1-Ethyl-2,2-dimethyl-propoxymethyl)-2-(hydroxyi...)
Affinity DataIC50:  2.40E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020535(1-Hexyloxymethyl-2-(hydroxyimino-methyl)-3-methyl-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020533(1-(1-Cyclohexyl-ethoxymethyl)-2-(hydroxyimino-meth...)
Affinity DataIC50:  2.60E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020518(1-Butoxymethyl-2-(hydroxyimino-methyl)-3-methyl-3H...)
Affinity DataIC50:  2.75E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020529(2-(Hydroxyimino-methyl)-3-methyl-1-(3-phenyl-propo...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020530(2-(Hydroxyimino-methyl)-3-methyl-1-(1,3,3-trimethy...)
Affinity DataIC50:  3.25E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020531(2,3-Dimethyl-1-(1,2,2-trimethyl-propoxymethyl)-3H-...)
Affinity DataIC50:  3.30E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Mus musculus)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020515(2-(Hydroxyimino-methyl)-3-methyl-1-(naphthalen-1-y...)
Affinity DataIC50:  3.50E+4nMAssay Description:Compound was tested for the binding affinity towards muscarinic receptor in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367852(CHEMBL538352)
Affinity DataIC50:  3.80E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020528(1-Cyclohexylmethoxymethyl-2-(hydroxyimino-methyl)-...)
Affinity DataIC50:  4.20E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020518(1-Butoxymethyl-2-(hydroxyimino-methyl)-3-methyl-3H...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020527(2-(Hydroxyimino-methyl)-1,3-dimethyl-3H-benzoimida...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020520(2-(Hydroxyimino-methyl)-1-isopropoxymethyl-3-methy...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020520(2-(Hydroxyimino-methyl)-1-isopropoxymethyl-3-methy...)
Affinity DataIC50:  4.90E+4nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50020523(1-Benzyloxymethyl-2-(hydroxyimino-methyl)-3-methyl...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025239(3-Benzyl-N-hydroxy-[1,2,4]oxadiazole-5-carboximido...)
Affinity DataIC50:  5.50E+4nMAssay Description:In vitro reversible inhibition of eel acetylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International

Curated by ChEMBL
LigandPNGBDBM50025239(3-Benzyl-N-hydroxy-[1,2,4]oxadiazole-5-carboximido...)
Affinity DataIC50:  5.50E+4nMAssay Description:In vitro reversible inhibition of eel acetylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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