Affinity DataKi: 0.00420nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0150nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00260nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00620nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0340nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to rat A 10 cells which express endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibitory activity against ACAT in rat macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to human GH cells which express endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibitory activity against ACAT in rat macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against ACAT in rat macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against ACAT in rat macrophagesMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against ACAT in rat macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to human GH cells which express endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to human GH cells which express endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Tested in vitro for inhibition of Endothelin-converting enzyme (ECE) of rat lung membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against ACAT in rat macrophagesMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against ACAT in rat macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair