TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to FLT3 (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to wild type BCR-ABL (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Binding affinity to wild type BCR-ABL T315I mutant (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of recombinant wild type Abl (unknown origin) in presence of [33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Binding affinity to human recombinant His-tagged full length ABL1 expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of wild type Abl (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of wild type BCR-ABL phosphorylation in mouse BaF3 cells incubated for 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of BCR-ABL phosphorylation in human K562 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant PDGFRalpha (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BCR-ABL phosphorylation in human K562 cells incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant Abl-T315I mutant (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) in presence of [33P]-ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair