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Found 389 with Last Name = 'pinney' and Initial = 'kg'
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330030(CHEMBL1269632 | [(3-Bromophenyl)-(3-hydroxyphenyl)...)
Affinity DataKi:  3.70nMAssay Description:Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50232473(CHEMBL4087627)
Affinity DataKi:  8.40nMAssay Description:Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50128821(CHEMBL3629203)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM138145(US8877967, 11)
Affinity DataIC50:  8.12nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50128809(CHEMBL3629191)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM138142(US8877967, 3)
Affinity DataIC50:  10.5nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50128812(CHEMBL3629194)
Affinity DataIC50:  14nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50189273(1-(7-bromo-3,4-dihydronaphthalen-1(2H)-ylidene)thi...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Oxigene

US Patent
LigandPNGBDBM138142(US8877967, 3)
Affinity DataIC50:  17.4nMpH: 3.5 T: 2°CAssay Description:Recombinant human procathepsin K was obtained from Enzo Life Sciences. Activation of the proenzyme was performed in 32.5 mM sodium acetate pH 3.5, ED...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM138143(US8877967, 6)
Affinity DataIC50:  23.8nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCruzipain(Trypanosoma cruzi)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50189279(1-(bis(3-bromophenyl)methylene)thiosemicarbazide |...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50128811(CHEMBL3629193)
Affinity DataIC50:  24nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM138146(US8877967, 13)
Affinity DataIC50:  24.3nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM138154(US8877967, 25)
Affinity DataIC50:  25nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306641(CHEMBL589280 | [(3-Bromophenyl)-(2-fluorophenyl)-k...)
Affinity DataIC50:  30.5nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388838(CHEMBL2062897)
Affinity DataIC50:  46nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306647(CHEMBL601890 | [(3-Bromophenyl)-(3-trifluoromethyl...)
Affinity DataIC50:  46.5nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50128810(CHEMBL3629192)
Affinity DataIC50:  56nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306656(CHEMBL600860 | [(3-Bromophenyl)-(2,4-difluoropheny...)
Affinity DataIC50:  59.4nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306662(CHEMBL602934 | [(3-Bromophenyl)-(2,3,4,5-tetrafluo...)
Affinity DataIC50:  63.2nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388851(CHEMBL2062909)
Affinity DataIC50:  68nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50128820(CHEMBL3629202)
Affinity DataIC50:  72nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306649(CHEMBL602093 | [(3-Bromophenyl)-(4-fluorophenyl)-k...)
Affinity DataIC50:  79.6nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50189280(1-((3-bromophenyl)(phenyl)methylene)thiosemicarbaz...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306654(CHEMBL601644 | [(3-Bromophenyl)-(2,3-difluoropheny...)
Affinity DataIC50:  83.8nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306658(CHEMBL603084 | [(3-Bromophenyl)-(2,4-ditrifluorome...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50189271(1-(6-bromo-2,3-dihydrochromen-4-ylidene)thiosemica...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388835(CHEMBL2062926)
Affinity DataIC50:  112nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306660(CHEMBL603085 | [(3-Bromophenyl)-(3-bromo,4-fluorop...)
Affinity DataIC50:  114nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306661(CHEMBL599998 | [(3-Bromophenyl)-(3,4,5-trifluoroph...)
Affinity DataIC50:  118nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330034(Bis(3-bromophenyl)(4-hydroxy)thiosemicarbazone | C...)
Affinity DataIC50:  126nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306646(CHEMBL606452 | [(3-Bromophenyl)-(3-chlorophenyl)-k...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330030(CHEMBL1269632 | [(3-Bromophenyl)-(3-hydroxyphenyl)...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330031(CHEMBL1272261 | [(3-Bromophenyl)-(3-acetoxyphenyl)...)
Affinity DataIC50:  151nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388837(CHEMBL2062896)
Affinity DataIC50:  152nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50491138(CHEMBL2376019)
Affinity DataIC50:  164nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50232473(CHEMBL4087627)
Affinity DataIC50:  202nMAssay Description:Inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured at 15 sec interval ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50189278(6-bromo-2,3-dihydro-4H-thiochromen-4-one thiosemic...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388842(CHEMBL2062901)
Affinity DataIC50:  214nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306648(CHEMBL602092 | [(3-Bromophenyl)-m-tolyl-ketone]thi...)
Affinity DataIC50:  224nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM87123(3,4-bis(fluoranyl)-N-[2-[1-(3-fluorophenyl)-4-oxid...)
Affinity DataIC50:  228nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50491134(CHEMBL2376003)
Affinity DataIC50:  228nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330036(Bis(3-bromophenyl)(5-hydroxy)thiosemicarbazone | C...)
Affinity DataIC50:  232nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306659(CHEMBL602683 | [(3-Bromophenyl)-(3-bromo,2-fluorop...)
Affinity DataIC50:  233nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306645(CHEMBL605998 | [(3-Bromophenyl)-(3-fluorophenyl)-k...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388848(CHEMBL2062907)
Affinity DataIC50:  256nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388832(CHEMBL2062923)
Affinity DataIC50:  260nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50388847(CHEMBL2062906)
Affinity DataIC50:  284nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50306650(CHEMBL602094 | [(3-Bromophenyl)-(4-chlorophenyl)-k...)
Affinity DataIC50:  327nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50491155(CHEMBL2376004)
Affinity DataIC50:  338nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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