Affinity DataKi: 3.70nMAssay Description:Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.12nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10.5nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 17.4nMpH: 3.5 T: 2°CAssay Description:Recombinant human procathepsin K was obtained from Enzo Life Sciences. Activation of the proenzyme was performed in 32.5 mM sodium acetate pH 3.5, ED...More data for this Ligand-Target Pair
Affinity DataIC50: 23.8nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24.3nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Affinity DataIC50: 30.5nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 46.5nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59.4nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 63.2nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured every 15 sec for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79.6nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 83.8nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 131nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 131nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 164nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...More data for this Ligand-Target Pair
Affinity DataIC50: 202nMAssay Description:Inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured at 15 sec interval ...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of Trypanosoma cruzi recombinant cruzainMore data for this Ligand-Target Pair
Affinity DataIC50: 214nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 233nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 256nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 284nMAssay Description:Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataIC50: 327nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 338nMAssay Description:Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...More data for this Ligand-Target Pair