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Found 699 with Last Name = 'potter' and Initial = 'bv'
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532058(CHEMBL4064554)
Affinity DataKi:  2nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)
Affinity DataKi:  8nMAssay Description:Inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataKi:  10nMAssay Description:Inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  12nMAssay Description:Inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  25nMAssay Description:Inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)
Affinity DataKi:  25nMAssay Description:Inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132166(1,2,4,5-InsP4 | CHEMBL100498 | Phosphoric acid mon...)
Affinity DataKi:  26.4nMAssay Description:Compound was evaluated for its ability to displace [3H]Ins(1,4,5)P3 from membranes prepared from bovine adrenal corticlesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataKi:  30nMAssay Description:Inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)
Affinity DataKi:  34nMAssay Description:Inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataKi:  37nMAssay Description:Inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50200936((9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,...)
Affinity DataKi:  70nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532053(CHEMBL3622044)
Affinity DataKi:  80nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50200941((9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),...)
Affinity DataKi:  232nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50200941((9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),...)
Affinity DataKi:  250nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532057(CHEMBL4550943)
Affinity DataKi:  260nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50200936((9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,...)
Affinity DataKi:  270nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532058(CHEMBL4064554)
Affinity DataKi:  340nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50469035(CHEMBL4282693)
Affinity DataKi:  440nMAssay Description:Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50430584(CHEMBL2337806)
Affinity DataKi:  440nMAssay Description:Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532054(CHEMBL4468079)
Affinity DataKi:  450nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50372895(CHEMBL408967)
Affinity DataKi:  750nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50121070(CHEMBL3622017)
Affinity DataKi:  770nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532060(CHEMBL4547186)
Affinity DataKi:  860nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  900nMAssay Description:Inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532056(CHEMBL4104342)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50200940((13ALPHA,14BETA,17ALPHA)-3-HYDROXY-2-METHOXYESTRA-...)
Affinity DataKi:  1.18E+3nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50372895(CHEMBL408967)
Affinity DataKi:  1.47E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50200941((9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),...)
Affinity DataKi:  2.42E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532060(CHEMBL4547186)
Affinity DataKi:  4.44E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532056(CHEMBL4104342)
Affinity DataKi:  4.73E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50586357(CHEMBL5080660)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532057(CHEMBL4550943)
Affinity DataKi:  5.31E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532053(CHEMBL3622044)
Affinity DataKi:  8.64E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50200940((13ALPHA,14BETA,17ALPHA)-3-HYDROXY-2-METHOXYESTRA-...)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366322(CHEMBL2367489)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity against estrone sulfatase in placental preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532055(CHEMBL4567341)
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279840((D)-2,2-difluoro-2-deoxy-myo-inositol 1,4,5-tripho...)
Affinity DataKi:  2.60E+4nMAssay Description:Compound was evaluated for binding affinity towards Inositol-1,4,5-trisphosphate 5-phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366322(CHEMBL2367489)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity against estrone sulfatase in breast tumor preparationsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532055(CHEMBL4567341)
Affinity DataKi:  5.19E+4nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532054(CHEMBL4468079)
Affinity DataKi:  6.96E+4nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50532059(CHEMBL4086075)
Affinity DataKi:  9.06E+4nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1/2/3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211666(CHEMBL1161456)
Affinity DataKi:  2.92E+5nMAssay Description:Compound was evaluated for its ability to inhibit Inositol phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532059(CHEMBL4086075)
Affinity DataKi:  6.79E+5nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol-trisphosphate 3-kinase C(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50040911((+)-myo-inositol 1,4,5-trisphosphorothioate | (-)-...)
Affinity DataKi:  9.78E+5nMAssay Description:Tested for the ability to inhibit Ins(1,4,5)P 3-phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50147505((2S,4aS,6aS,6bR,10S,12aS,14bR)-10-Hydroxy-2,4a,6a,...)
Affinity DataIC50:  0.00400nMAssay Description:Percent inhibition against 11-beta-hydroxysteroid dehydrogenase 2 of wistar rat kidney at 10 microM was determined using [3H]-cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380208(CHEMBL2011408)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50121196(CHEMBL3622029)
Affinity DataIC50:  0.0350nMAssay Description:Inhibition of STS activity in human JEG-3 cells by liquid scintillation spectrometry in presence of [6,7-3H]estrone3-sulfateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380223(CHEMBL2011422)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of steroid sulfatase in human placental microsomes using [3H]E1S as substrate after 30 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307918(2-(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380216(CHEMBL364332)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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