Affinity DataKi: 2nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 26.4nMAssay Description:Compound was evaluated for its ability to displace [3H]Ins(1,4,5)P3 from membranes prepared from bovine adrenal corticlesMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 232nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia
Curated by ChEMBL
University Of East Anglia
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia
Curated by ChEMBL
University Of East Anglia
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assayMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 770nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 860nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+3nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.47E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.42E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.44E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.73E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia
Curated by ChEMBL
University Of East Anglia
Curated by ChEMBL
Affinity DataKi: 4.90E+3nMAssay Description:Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.31E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.64E+3nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+4nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Binding affinity against estrone sulfatase in placental preparationMore data for this Ligand-Target Pair
Affinity DataKi: 1.85E+4nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+4nMAssay Description:Compound was evaluated for binding affinity towards Inositol-1,4,5-trisphosphate 5-phosphataseMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Binding affinity against estrone sulfatase in breast tumor preparationsMore data for this Ligand-Target Pair
Affinity DataKi: 5.19E+4nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.96E+4nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.06E+4nMAssay Description:Inhibition of carbonic anhydrase 9 (unknown origin) expressed in Escherichia coli BL21 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.92E+5nMAssay Description:Compound was evaluated for its ability to inhibit Inositol phosphorylationMore data for this Ligand-Target Pair
Affinity DataKi: 6.79E+5nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.78E+5nMAssay Description:Tested for the ability to inhibit Ins(1,4,5)P 3-phosphataseMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
University Of Bath
Curated by ChEMBL
University Of Bath
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:Percent inhibition against 11-beta-hydroxysteroid dehydrogenase 2 of wistar rat kidney at 10 microM was determined using [3H]-cortisolMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of STS activity in human JEG-3 cells by liquid scintillation spectrometry in presence of [6,7-3H]estrone3-sulfateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of steroid sulfatase in human placental microsomes using [3H]E1S as substrate after 30 mins by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair