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Found 166 with Last Name = 'quesnelle' and Initial = 'ca'
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445507(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(4-fl...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445512(US10683290, Example 8)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445515(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-9-fluoro-5-[...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445517(2-[9-Chloro-7-(dimethyl-1H-1,2,3-triazol-5-yl)-5-[...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445529(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445530(2-{8-Fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)meth...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445533(5-{8-Fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)meth...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445536(5-{8-Fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)meth...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445538(2-{8-Fluoro-5-[(3-fluoropyridin-2-yl)(oxan-4-yl)me...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445540(2-{8-Fluoro-7-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445541(2-{8-Fluoro-7-[5-(2H3)methyl-3-methyl-1,2-oxazol-4...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445542(2-{8-Fluoro-5-[(5-methyl-1,2-oxazol-3-yl)(oxan-4-y...)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445544(US10683290, Example 36)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445545(US10683290, Example 38)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445567(US10683290, Example 66)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445578(US10683290, Example 71)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445579(US10683290, Example 72)
Affinity DataIC50: <1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209895(US9273014, 24)
Affinity DataIC50:  1.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209891(US9273014, 20)
Affinity DataIC50:  1.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209891(US9273014, 20)
Affinity DataIC50:  1.60nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209896(US9273014, 25)
Affinity DataIC50:  1.70nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209874(US9273014, 3)
Affinity DataIC50:  1.80nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209874(US9273014, 3)
Affinity DataIC50:  1.90nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209895(US9273014, 24)
Affinity DataIC50:  2.10nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209876(US9273014, 5)
Affinity DataIC50:  2.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209888(US9273014, 17)
Affinity DataIC50:  2.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209881(US9273014, 10)
Affinity DataIC50:  2.5nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209898(US9273014, 27)
Affinity DataIC50:  2.70nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209898(US9273014, 27)
Affinity DataIC50:  2.80nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209902(US9273014, 31)
Affinity DataIC50:  2.80nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209896(US9273014, 25)
Affinity DataIC50:  2.90nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209880(US9273014, 11 | US9273014, 9)
Affinity DataIC50:  3nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209883(US9273014, 12)
Affinity DataIC50:  3nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209907(US9273014, 36)
Affinity DataIC50:  3nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209893(US9273014, 22)
Affinity DataIC50:  3.10nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209883(US9273014, 12)
Affinity DataIC50:  3.20nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209892(US9273014, 21)
Affinity DataIC50:  3.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209884(US9273014, 13)
Affinity DataIC50:  3.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209897(US9273014, 26)
Affinity DataIC50:  3.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209897(US9273014, 26)
Affinity DataIC50:  3.70nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209880(US9273014, 11 | US9273014, 9)
Affinity DataIC50:  3.70nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209887(US9273014, 16)
Affinity DataIC50:  3.70nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209900(US9273014, 29)
Affinity DataIC50:  3.90nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209876(US9273014, 5)
Affinity DataIC50:  4nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209890(US9273014, 19)
Affinity DataIC50:  4nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209901(US9273014, 30 | US9273014, 35)
Affinity DataIC50:  4.20nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209904(US9273014, 33)
Affinity DataIC50:  4.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209871(US9273014, 2)
Affinity DataIC50:  4.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209901(US9273014, 30 | US9273014, 35)
Affinity DataIC50:  4.30nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM209878(US9273014, 7)
Affinity DataIC50:  4.40nMAssay Description:The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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