Affinity DataKi: 6nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 15nM ΔG°: -44.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Competitive inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate by Dixon plot analys...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 21nM ΔG°: -43.8kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -43.5kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -43.5kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 28nM ΔG°: -43.1kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 34nM ΔG°: -42.6kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 39nM ΔG°: -42.3kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 45nM ΔG°: -41.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 46nM ΔG°: -41.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Competitive inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate by Dixon plot analys...More data for this Ligand-Target Pair
Affinity DataKi: 65nM ΔG°: -41.0kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 104nM ΔG°: -39.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 107nM ΔG°: -39.8kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 110nM ΔG°: -39.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 230nM ΔG°: -37.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -37.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 290nM ΔG°: -37.3kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 300nM ΔG°: -37.2kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 300nM ΔG°: -37.2kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 800nM ΔG°: -35.0kJ/mole IC50: 1.10E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 820nM ΔG°: -34.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 900nM ΔG°: -34.7kJ/mole IC50: 4.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 900nM ΔG°: -34.7kJ/mole IC50: 7.60E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, the concentrations of inhibitor that caused 50% inhibition of enzymati...More data for this Ligand-Target Pair
Affinity DataKi: 900nM ΔG°: -34.7kJ/mole IC50: 8.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nM ΔG°: -34.2kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nM ΔG°: -34.2kJ/mole IC50: 3.70E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nM ΔG°: -34.0kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nM ΔG°: -33.5kJ/mole IC50: 3.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nM ΔG°: -33.3kJ/mole IC50: 1.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nM ΔG°: -33.3kJ/mole IC50: 2.90E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, the concentrations of inhibitor that caused 50% inhibition of enzymati...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nM ΔG°: -33.0kJ/mole IC50: 8.70E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nM ΔG°: -32.6kJ/mole IC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nM ΔG°: -32.3kJ/mole IC50: 2.90E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nM ΔG°: -32.3kJ/mole IC50: 5.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nM ΔG°: -32.2kJ/mole IC50: 3.30E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair