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Found 266 with Last Name = 'ranasinghe' and Initial = 'a'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011322(CHEMBL3260745)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011324(CHEMBL3260747)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011328(CHEMBL3259829)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011326(CHEMBL3260748)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011330(CHEMBL3260750)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011323(CHEMBL3260746)
Affinity DataKi:  3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011334(CHEMBL3260754)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011310(CHEMBL3260737)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011316(CHEMBL3260743)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011333(CHEMBL3260753)
Affinity DataKi:  4.70nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011331(CHEMBL3260751)
Affinity DataKi:  5nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011332(CHEMBL3260752)
Affinity DataKi:  5nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011317(CHEMBL3260744)
Affinity DataKi:  8.40nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011314(CHEMBL3260741)
Affinity DataKi:  9nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011307(CHEMBL3260734)
Affinity DataKi:  10nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011329(CHEMBL3260749)
Affinity DataKi:  12nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50356013(CHEMBL1911374 | CHEMBL1911375)
Affinity DataKi:  12nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011315(CHEMBL3260742)
Affinity DataKi:  15nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011309(CHEMBL3260736)
Affinity DataKi:  18nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011313(CHEMBL3260740)
Affinity DataKi:  28nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011312(CHEMBL3260739)
Affinity DataKi:  29nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011336(CHEMBL3260756)
Affinity DataKi:  77nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011335(CHEMBL3260755)
Affinity DataKi:  92nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011306(CHEMBL3260733)
Affinity DataKi:  210nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011311(CHEMBL3260738)
Affinity DataKi:  214nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50011308(CHEMBL3260735)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566615(CHEMBL4846895)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566615(CHEMBL4846895)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297163(2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566614(CHEMBL4848871)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074694(CHEMBL3410161)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch2 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074799(CHEMBL3410167)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074771(CHEMBL3410153)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074818(CHEMBL3410163)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566613(CHEMBL4864173)
Affinity DataIC50:  1nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074796(CHEMBL3410169)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566614(CHEMBL4848871)
Affinity DataIC50:  1nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074771(CHEMBL3410153)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50586606(CHEMBL5080354)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNeurogenic locus notch homolog protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074693(CHEMBL3410162)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50074796(CHEMBL3410169)
Affinity DataIC50:  1nMAssay Description:Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human BRD3 measured by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566613(CHEMBL4864173)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM297146(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human BRD2 measured by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566612(CHEMBL4869203)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50586604(CHEMBL5093440)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM296886(2-[3-(Dimethyl-1,2-oxazol-4-yl)-5-[oxan-4-yl(pheny...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human BRD2 measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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