Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human N-terminal maltase-glucoamylaseMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataKi: 302nMAssay Description:Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of human recombinant N-terminal maltase-glucoamylase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of human N-terminal maltase-glucoamylaseMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 550nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 670nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 2.33E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 3.25E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataKi: 4.15E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.00E+4nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.65E+5nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Ecole Polytechnique FéDéRale De Lausanne
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity for SH2 domain of src in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Affinity for SH2 domain of src in Sf9 insect cellsMore data for this Ligand-Target Pair