TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1(Mus musculus)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 6.30E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GpYDKPHVL-NH2 from mouse recombinant His-tagged STAT1-SH2 domain expressed in Escherichia coli BL21 (DE3) by flu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 1.28E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 1.33E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of mouse STAT3 SH2 domain using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 30 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 1.55E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1(Mus musculus)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.65E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYDKPHVL-NH2 from mouse recombinant His-tagged STAT1-SH2 domain expressed in Escherichia coli BL21 (DE3) by flu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.30E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1(Mus musculus)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse STAT1 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 30 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.60E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 2.65E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 3.06E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 3.60E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 3.80E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: 4.10E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Homo sapiens)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of C-terminal recombinant human ClpP expressed in Escherichia coli Rosetta2 (DE3) cells using Suc-Leu-Tyr-AMC as substrate incubated for 1...More data for this Ligand-Target Pair
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Homo sapiens)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of C-terminal recombinant human ClpP (57 to 277 amino acids) expressed in Escherichia coli Rosetta2 cells using Suc-Leu-Tyr-AMC as substra...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Homo sapiens)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of human ClpP expressed in Escherichia coli SG1146 cells using N-acetyl-Trp-Leu-Ala-AMC as substrate incubated for 1 hr and measured at 20...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Binding affinity to Stat1 (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after 30 mins by fluorescenc...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Binding affinity to Stat3 (unknown origin) using hSIE as probe preincubated for 30 mins followed by hSIE addition by electrophoretic mobility shift a...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Homo sapiens)
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human ClpP expressed in Escherichia coli SG1146 cells using N-acetyl-Trp-Leu-Ala-AMC as substrate incubated for 1 hr and measured at 20...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 9.20E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 9.40E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair