Affinity DataKi: 39nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 4.20E+3nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 1.64E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of Leishmania major recombinant PTR1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant mTOR assessed as inhibition of 4EBP1 phosphorylation after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human PI3K-delta assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human PI3K-alpha assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague
Curated by ChEMBL
Charles University In Prague
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of ABAD (unknown origin) assessed as residual activity using acetoacetyl-CoA in presence of NADH by spectrophotometric assay relative to c...More data for this Ligand-Target Pair
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
Charles University In Prague
Curated by ChEMBL
Charles University In Prague
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of ABAD (unknown origin) by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human PI3K-gamma assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of human PI3K-gamma assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of human PI3K-gamma assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Charles University In Prague
Curated by ChEMBL
Charles University In Prague
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human membrane bound MAO-B expressed in insect cell membranes assessed as reduction in conversion of kynuramine to 4-hydroxyquinoline b...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of human PI3K-beta assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of human PI3K-gamma assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant mTOR assessed as inhibition of 4EBP1 phosphorylation after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of human PI3K-alpha assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 468nMAssay Description:Inhibition of human recombinant mTOR assessed as inhibition of 4EBP1 phosphorylation after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Inhibition of human PI3K-alpha assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 631nMAssay Description:Inhibition of human PI3K-alpha assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 794nMAssay Description:Inhibition of human PI3K-delta assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of horse radish peroxidase assessed as residual activity by amplex red dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of horse radish peroxidase assessed as residual activity by amplex red dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of horse radish peroxidase assessed as residual activity by amplex red dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of horse radish peroxidase assessed as residual activity by amplex red dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of horse radish peroxidase assessed as residual activity by amplex red dye based fluorescence assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human recombinant mTOR assessed as inhibition of 4EBP1 phosphorylation after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human recombinant mTOR assessed as inhibition of 4EBP1 phosphorylation after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human PI3K-gamma assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human PI3K-delta assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human PI3K-delta assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Charles University In Prague
Curated by ChEMBL
Charles University In Prague
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human membrane bound MAO-B expressed in insect cell membranes assessed as reduction in conversion of kynuramine to 4-hydroxyquinoline b...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human PI3K-alpha assessed as inhibition of Ptdlns(3,4,5)P3 phosphorylation after 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Charles University In Prague
Curated by ChEMBL
Charles University In Prague
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human membrane bound MAO-B expressed in insect cell membranes assessed as reduction in conversion of kynuramine to 4-hydroxyquinoline b...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Charles University In Prague
Curated by ChEMBL
Charles University In Prague
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human membrane bound MAO-B expressed in insect cell membranes assessed as reduction in conversion of kynuramine to 4-hydroxyquinoline b...More data for this Ligand-Target Pair