Found 26 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM92862' 
Affinity DataKi: 1.70nM ΔG°: -50.1kJ/mole IC50: 3.90nMT: 2°CAssay Description:The LanthaScreen TR-FRET mTOR assay was performed using Costar low-binding 284-well plates at room temperature according to the instructions of the m...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nM IC50: 9.60nMAssay Description:The mTOR activity was determined by measuring the amount of [gamma-33 P] phosphae from ATP incorporated in the substrate protein.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) using Ulight-4E-BP1 as substrate incubated for 30 mins by fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of Alexa Fluor labelled Tracer-314 from human N-terminal GST-tagged mTOR incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant mTOR using substrate PI incubated for 1 hr by Adapta kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.23nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents {circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 10 mM MgCl2, 1 mM EGTA, 3 mM MnCl, 0.01% Tween-20, 2 mM DT...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant mTOR assessed as inhibition of 4EBP1 phosphorylation after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human mTOR after 60 mins in presence of [gamma-33P]-ATP by microplate scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Binding affinity to human N-terminal GST-tagged mTOR assessed as phosphorylated 4EBP1 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin) using GFP-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362-end residues) using ULight-4E-BP1 peptide substrate after 1 hr in presence of ATP b...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin) expressed in baculovirus after 60 mins by kinase-glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr by lance ultra assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin) by K-LISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human mTOR (1362 to end residue) using ULight-4EBP1 peptide as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction of ATP level after 40 mins by luciferase based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of mTOR (unknown origin) using L-alpha-phosphatidylinositol as substrate after 40 mins by ATP depletion assayMore data for this Ligand-Target Pair
