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Found 65 with Last Name = 'strakhova' and Initial = 'mi'
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50247054(6-(3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azep...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(CHEMBL1277595 | N-Methyl-4-phenyl-4-(4-(2-(pyrroli...)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415770(CHEMBL1079516)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415770(CHEMBL1079516)
Affinity DataKi:  1.51nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415769(CHEMBL1089390)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330792(CHEMBL1277686 | N-methyl-3-(naphthalen-1-yl)-3-phe...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415769(CHEMBL1089390)
Affinity DataKi:  2.63nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415767(CHEMBL1077276)
Affinity DataKi:  2.69nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(CHEMBL1277595 | N-Methyl-4-phenyl-4-(4-(2-(pyrroli...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415768(CHEMBL1089040)
Affinity DataKi:  3.24nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26226((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)
Affinity DataKi:  3.40nM ΔG°:  -48.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  4.47nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataKi:  4.70nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26226((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)
Affinity DataKi:  5.80nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415770(CHEMBL1079516)
Affinity DataKi:  6.76nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  7nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415767(CHEMBL1077276)
Affinity DataKi:  7.08nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataKi:  12nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26226((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)
Affinity DataKi:  13.5nM ΔG°:  -44.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(CHEMBL1277595 | N-Methyl-4-phenyl-4-(4-(2-(pyrroli...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Affinity DataKi:  20nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26400(2,4-diamino-5,6-disubstituted pyrimidine, 14 | 9-p...)
Affinity DataKi:  39.8nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330786(CHEMBL1277410 | N-Methyl-3-phenyl-3-(6-(2-(pyrroli...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415768(CHEMBL1089040)
Affinity DataKi:  49.0nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415770(CHEMBL1079516)
Affinity DataKi:  63.1nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(CHEMBL1277595 | N-Methyl-4-phenyl-4-(4-(2-(pyrroli...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415769(CHEMBL1089390)
Affinity DataKi:  72.4nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415771(CHEMBL1081680)
Affinity DataKi:  79.4nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415768(CHEMBL1089040)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415769(CHEMBL1089390)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415768(CHEMBL1089040)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330786(CHEMBL1277410 | N-Methyl-3-phenyl-3-(6-(2-(pyrroli...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50415771(CHEMBL1081680)
Affinity DataKi:  295nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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