Affinity DataKi: 1.10nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 22.1nMAssay Description:Displacement of [3H]-WIN-35428 from human DAT expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22.1nMAssay Description:Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 127nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 332nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 521nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 525nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 525nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 714nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: 3.13E+3nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Antagonistic activity against Progesterone receptor (PR) in transcriptional activation assay in human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against progesterone receptor (PR) using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at glucocorticoid receptor by Gal4-DNA binding domain-hormone receptor LBD one-hybrid assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at cloned glucocorticoid receptor-ligand binding domain expressed in african green monkey COS7 cells by GAL4 luciferase reporter ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]progesterone from progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cells assessed as inhibition of norepinephrine uptakeMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]P4 to progesterone receptor (PR) of human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cells assessed as inhibition of norepinephrine uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]progesterone from progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair