BindingDB PrimarySearch_ki

Found 476 with Last Name = 'tesch' and Initial = 'r'

Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

PNG

BDBM50601538(CHEMBL5090394)

IC50: 0.300nMAssay Description:Inhibition of GST-tagged human SIK2 autophosphorylation measured after 30 mins in presence of [gamma33P]ATP by Western blot analysisMore data for this Ligand-Target Pair

UniProtKB/SwissProt
antibodypedia GoogleScholar

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Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Technical University of Dortmund

PNG

BDBM153732(K252a)

IC50: <1nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

PNG

BDBM50601534(CHEMBL4539742)

IC50: 1nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair

UniProtKB/SwissProt
antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50331622(5-amino-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl...)

IC50: 2nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL

PNG

BDBM50585185(CHEMBL5077814)

IC50: 2nMAssay Description:Inhibition of recombinant human GSK-3-beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL

PNG

BDBM50585185(CHEMBL5077814)

IC50: 2nMAssay Description:Inhibition of recombinant human GSK-3-beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Technical University of Dortmund

PNG

BDBM153755(ROCHE screening, 77)

IC50: 3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524536(CHEMBL4452170)

IC50: 3nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505859(CHEMBL4436748)

IC50: 3.70nMAssay Description:Inhibition of full-length human C-terminal NanoLuc-tagged P38 alpha MAPK expressed in human HEK293T cells incubated for 2 hrs followed by NanoBRET Na...More data for this Ligand-Target Pair

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3D Structure (crystal)

Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

PNG

BDBM50148921(CHEMBL3770443)

IC50: 4.40nMAssay Description:Inhibition of GST-tagged human SIK2 autophosphorylation measured after 30 mins in presence of [gamma33P]ATP by Western blot analysisMore data for this Ligand-Target Pair

UniProtKB/SwissProt
antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505859(CHEMBL4436748)

IC50: 5nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

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3D Structure (crystal)

Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50492374(CHEMBL2401983)

IC50: 5nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

PNG

BDBM50601534(CHEMBL4539742)

IC50: 6nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL

PNG

BDBM50585181(CHEMBL5089934)

IC50: 6nMAssay Description:Inhibition of recombinant human GSK-3-beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL

PNG

BDBM50585181(CHEMBL5089934)

IC50: 6.30nMAssay Description:Inhibition of recombinant human GSK-3-beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505874(CHEMBL4444997)

IC50: 9nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 11(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505859(CHEMBL4436748)

IC50: 10nMAssay Description:Inhibition of p38-beta (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBR...More data for this Ligand-Target Pair

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Mitogen-activated protein kinase 11(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50331622(5-amino-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl...)

IC50: 10nMAssay Description:Inhibition of recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP bas...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Technical University of Dortmund

PNG

BDBM10111((3Z)-5-fluoro-4-[2-(4-hydroxypiperidin-4-yl)ethyny...)

IC50: 12nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505885(CHEMBL4473671)

IC50: 13nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524531(CHEMBL4513323)

IC50: 13nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524523(CHEMBL4446519)

IC50: 14nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505875(CHEMBL4443551)

IC50: 14nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524518(CHEMBL4442468)

IC50: 15nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505903(CHEMBL4462636)

IC50: 15nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524519(CHEMBL4434855)

IC50: 15nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524537(CHEMBL4536012)

IC50: 16nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505900(CHEMBL4449421)

IC50: 17nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505899(CHEMBL4552734)

IC50: 17nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524521(CHEMBL4446355)

IC50: 18nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505888(CHEMBL4476320)

IC50: 18nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524538(CHEMBL4476724)

IC50: 18nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL

PNG

BDBM50524514(CHEMBL4474903)

IC50: 18nMAssay Description:Competitive inhibition of human recombinant full length GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated with enzyme for 10 min...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524529(CHEMBL4476843)

IC50: 18nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524527(CHEMBL4455711)

IC50: 19nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524541(CHEMBL4457096)

IC50: 19nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524535(CHEMBL4437018)

IC50: 20nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524532(CHEMBL4458096)

IC50: 20nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524506(CHEMBL4473730)

IC50: 20nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524509(CHEMBL4571942)

IC50: 21nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Serine/threonine-protein kinase SIK1(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

PNG

BDBM50601534(CHEMBL4539742)

IC50: 21nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524511(CHEMBL4555253)

IC50: 22nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

PNG

BDBM50601538(CHEMBL5090394)

IC50: 22nMAssay Description:Inhibition of human SIK3 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524533(CHEMBL4566059)

IC50: 23nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL

PNG

BDBM50585180(CHEMBL5084461)

IC50: 23nMAssay Description:Inhibition of recombinant human GSK-3-beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524514(CHEMBL4474903)

IC50: 24nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Eberhard Karls University T£Bingen

Curated by ChEMBL

PNG

BDBM50585180(CHEMBL5084461)

IC50: 25nMAssay Description:Inhibition of recombinant human GSK-3-beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Technical University of Dortmund

PNG

BDBM153745(ROCHE screening, 59)

IC50: 26nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50505886(CHEMBL4574467)

IC50: 26nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Mitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL

PNG

BDBM50524528(CHEMBL4568095)

IC50: 27nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) using ATF-2 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Displayed 1 to 50 (of 476 total ) | Next | Last >>

Filter my 476 hits

Targets 25▿
- Mitogen-activated protein kinase 14 122
- Glycogen synthase kinase-3 beta 94
- Serine/threonine-protein kinase TBK1 83
- Mitogen-activated protein kinase 11 82
- Serine/threonine-protein kinase SIK2 24
- Serine/threonine-protein kinase SIK3 17
- Epidermal growth factor receptor 17
- Glycogen synthase kinase-3 alpha 6
- Serine/threonine-protein kinase SIK1 4
- Angiopoietin-1 receptor 2
- Myosin light chain kinase family member 4 2
- Discoidin domain-containing receptor 2 2
- Mast/stem cell growth factor receptor Kit 2
- Serine/threonine-protein kinase NLK 2
- Mitogen-activated protein kinase kinase kinase kinase 5 2
- Mitogen-activated protein kinase kinase kinase 2 2
- Epithelial discoidin domain-containing receptor 1 2
- Ribosomal protein S6 kinase alpha-6 2
- Serine/threonine-protein kinase 26 2
- Serine/threonine-protein kinase N3 2
- Dual specificity mitogen-activated protein kinase kinase 4 1
- Serine/threonine-protein kinase PAK 1 1
- Serine/threonine-protein kinase PAK 2 1
- Maternal embryonic leucine zipper kinase 1
- Serine/threonine-protein kinase PAK 3 1
- ...
Publications 6▿
- J Med Chem 62: 10757-10782 (2019) 176
- Eur J Med Chem 175: 309-329 (2019) 90
- ACS Chem Biol 10: 289-98 (2015) 83
- J Med Chem 64: 8142-8160 (2021) 60
- J Med Chem 65: 1283-1301 (2022) 50
- Eur J Med Chem 71: 1-14 (2014) 17
Institutions 6▿
- Johann Wolfgang Goethe-University 176
- Eberhard Karls Universit£T T£Bingen 90
- Technical University of Dortmund 83
- Johann Wolfgang Goethe University 60
- Eberhard Karls University T£Bingen 50
- Federal University Of Rio De Janeiro 17
Affinity: 0.30 to 4.4E+6 nM▿
- IC50 476
- Affinity ≤ nM
Xtal structures: 18
Docked structures: 0
Catalog Cmpds: 29