Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV1 integrase strand transfer by biochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against serotonin 5-hydroxytryptamine 1A receptor from mice.More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair