Affinity DataKi: 7nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in GMCSF-stimulated human TF1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in GMCSF-stimulated human TF1 cellsMore data for this Ligand-Target Pair