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Found 38 with Last Name = 'ukani' and Initial = 'r'
TargetToll-like receptor 2(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50315416((R)-3-((R)-2-Amino-3-((S)-3-hydroxy-1-methoxy-1-ox...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50315417(((R)-3-(2-((R)-2-Amino-3-hydroxypropanamido)ethylt...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330062(1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue-7 cells assessed as increase in NFkappaB activation by sAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue-7 cells assessed as increase in NFkappaB activation by sAP assayMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330064(2-(3-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinoli...)
Affinity DataEC50:  247nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue-7 cells assessed as increase in NFkappaB activation by sAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330065(CHEMBL1269158 | N-(9-(4-(3-(4-((4-amino-2-butyl-1H...)
Affinity DataEC50:  115nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue-7 cells assessed as increase in NFkappaB activation by sAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330066(3-(4-(2-(5-(3-(4-((4-amino-2-butyl-1H-imidazo[4,5-...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue-7 cells assessed as increase in NFkappaB activation by sAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339295(2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanamido)...)
Affinity DataEC50:  0.0270nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339296(2-((R)-4-Amino-4-carboxybutanamido)-6-dodecanamido...)
Affinity DataEC50:  0.550nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339297(2-((R)-4-Carboxy-4-dodecanamidobutanamido)-6-dodec...)
Affinity DataEC50:  0.580nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339298(2-Amino-6-((R)-4-carboxy-4-(dodecylamino)butanamid...)
Affinity DataEC50:  0.0230nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339299(2-Amino-6-((R)-4-carboxy-4-(dioctylamino)butanamid...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339300(2-Amino-6-((R)-4-carboxy-4-(dihexadecylamino)butan...)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339301(2-Amino-6-((R)-4-carboxy-4-(didodecylamino)butanam...)
Affinity DataEC50:  0.00150nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339302((2R)-5-((4-(2-Amino-4-oxo-4,5-dihydro-1H-imidazol-...)
Affinity DataEC50:  1.31nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339303(2-((R)-4-Carboxy-4-dodecanamidobutanamido)-6-guani...)
Affinity DataEC50:  0.622nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50361926(CHEMBL66165)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human CCR1 expressed in CHO cells by cellular dielectric spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339305(2-Amino-6-((R)-4-amino-5-oxo-5-(undecylamino)penta...)
Affinity DataEC50:  0.826nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339306(2-Amino-6-((R)-4-dodecanamido-5-oxo-5-(undecyloxy)...)
Affinity DataEC50:  0.134nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339307((15R)-10,6-Dibenzyl 15-Ethyl-2,2-dimethyl-4,12,17-...)
Affinity DataEC50:  0.238nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339308(2-Amino-6-((R)-4-dodecanamido-5-ethoxy-5-oxopentan...)
Affinity DataEC50:  0.0690nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339309(CHEMBL1689707 | Diethyl 2-Amino-6-((R)-4-amino-5-o...)
Affinity DataEC50:  0.181nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339310((2R)-5-((6-Amino-1,7-diethoxy-1,7-dioxoheptan-2-yl...)
Affinity DataEC50:  0.145nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339311(2-Amino-6-(4-dodecanamidobutanamido)heptanedioic A...)
Affinity DataEC50:  0.504nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339312(2-Amino-6-(5-oxo-5-(undecyloxy)pentanamido)heptane...)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339313(2-((R)-4-Carboxy-4-dodecanamidobutanamido)heptaned...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339314((R)-5-((5-Aminopentyl)amino)-2-dodecanamido-5-oxop...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339315((2R)-2-Dodecanamido-5-oxo-5-((2-oxoazepan-3-yl)ami...)
Affinity DataEC50:  1.73nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339316((R)-6-Amino-2-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339317((R)-2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339318((S)-6-Amino-2-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50:  0.570nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339319((S)-2-Amino-6-((R)-4-carboxy-4-dodecanamidobutanam...)
Affinity DataEC50:  0.960nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50344549(CHEMBL1778421 | Methyl 1-(4-((4-amino-2-butyl-1H-i...)
Affinity DataEC50:  269nMAssay Description:Agonist activity at human TLR7 transfected in HEK reporter cells assessed as NFkappaB induction by specific secreted alkaline phosphatease gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50344550((2R)-methyl 2-amino-5-((2S)-3-(1-(3-(4-((4-amino-2...)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human TLR7 transfected in HEK reporter cells assessed as NFkappaB induction by specific secreted alkaline phosphatease gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  528nMAssay Description:Agonist activity at human TLR7 transfected in HEK reporter cells assessed as NFkappaB induction by specific secreted alkaline phosphatease gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330061(1-(Biphenyl-4-ylmethyl)-2-butyl-1H-imidazo[4,5-c]q...)
Affinity DataEC50:  396nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue-7 cells assessed as increase in NFkappaB activation by sAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50330060(2-Butyl-1-(naphthalen-1-ylmethyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  396nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue-7 cells assessed as increase in NFkappaB activation by sAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50339304(2-Amino-6-((R)-4-amino-5-oxo-5-(undecyloxy)pentana...)
Affinity DataEC50:  0.0660nMAssay Description:Agonist activity at human NOD-1 expressed in human HEK293 cells assessed as NFkappaB induction by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed