Affinity DataKi: 1.80nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [125I]Angiotensin 4 from human recombinant IRAP expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.51nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 27.5nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30.4nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 41.1nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 52.5nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 55.0nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 56.2nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 62.4nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 64.2nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as clevage of substrate L-leucine-p-nitroanili...More data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 129nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair
Affinity DataKi: 141nMAssay Description:Inhibition of human recombinant APN expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataKi: 141nMAssay Description:Displacement of [3H]valsartan from human recombinant AT1 receptor expressed in CHO cells after 40 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 177nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 178nMAssay Description:Inhibition of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroanilineMore data for this Ligand-Target Pair