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Found 646 with Last Name = 'weber' and Initial = 'p'
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288632(Boropeptide | CHEMBL607008)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069922(Boropeptide analogue | CHEMBL102069)
Affinity DataKi:  0.0400nMAssay Description:Tested for the binding affinity against thrombinChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288632(Boropeptide | CHEMBL607008)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0410nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069922(Boropeptide analogue | CHEMBL102069)
Affinity DataKi:  0.0450nMAssay Description:Tested for selectivity against trypsinChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Compound was tested in vitro for inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069926(Boropeptide analogue | CHEMBL105137)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069928(Boropeptide analogue | CHEMBL102385)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288621((S)-1-[3-(2-Trifluoromethyl-benzyl)-benzoyl]-pyrro...)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288628((S)-1-(3-Benzo[1,3]dioxol-5-ylmethyl-benzoyl)-pyrr...)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000020(CHEMBL2448361)
Affinity DataKi: <0.100nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289586(3-Methyl-2'-sulfamoyl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288631((S)-1-[3-(3-Trifluoromethyl-benzyl)-benzoyl]-pyrro...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288405(CHEMBL95940 | N-[(1-Dihydroxyboranyl-4-guanidino-b...)
Affinity DataKi:  0.160nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288623((S)-1-[3-(2-Methoxy-phenylsulfanyl)-benzoyl]-pyrro...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288634((S)-1-(3-Benzyl-benzoyl)-pyrrolidine-2-carboxylic ...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084682(1-[3-(4-Carbamimidoyl-phenyl)-2-(2-methyl-1,2,3,4-...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288627((S)-1-[3-(4-Trifluoromethyl-benzyl)-benzoyl]-pyrro...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288629((S)-1-[3-(2-Bromo-benzyl)-benzoyl]-pyrrolidine-2-c...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288414(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.240nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288620(Boropeptide | CHEMBL3038261)
Affinity DataKi:  0.240nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288637((S)-1-[3-(2-Methyl-benzyl)-benzoyl]-pyrrolidine-2-...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288630((S)-1-(2-Phenoxy-benzoyl)-pyrrolidine-2-carboxylic...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069933(Boropeptide analogue | CHEMBL102916)
Affinity DataKi:  0.280nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288636((S)-1-(2-Benzyl-benzoyl)-pyrrolidine-2-carboxylic ...)
Affinity DataKi:  0.290nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069172(Boronate Ester analogue | CHEMBL423259)
Affinity DataKi:  0.300nMAssay Description:Inhibition against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069935(Boropeptide analogue | CHEMBL320213)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288615((3S,4R)-3-{(S)-2-[(R)-5-Amino-1-((1S,2S,6R,8S)-2,9...)
Affinity DataKi:  0.320nMAssay Description:Compound was evaluated for the inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069931(Boropeptide analogue | CHEMBL105212)
Affinity DataKi:  0.360nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50289591(2'-Diethylsulfamoyl-3-methyl-biphenyl-4-carboxylic...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288626((S)-1-(3-Phenoxy-benzoyl)-pyrrolidine-2-carboxylic...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069937(Boropeptide analogue | CHEMBL102779)
Affinity DataKi:  0.370nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069936(Boropeptide analogue | CHEMBL319050)
Affinity DataKi:  0.410nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288409(CHEMBL99309 | N-[(5-Amino-1-dihydroxyboranyl-penty...)
Affinity DataKi:  0.420nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288633((S)-1-[3-(4-Methoxy-phenylsulfanyl)-benzoyl]-pyrro...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069924(Boropeptide analogue | CHEMBL419734)
Affinity DataKi:  0.420nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50289587(3-Methyl-biphenyl-4-carboxylic acid [(R)-4-guanidi...)
Affinity DataKi:  0.420nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069930(Boropeptide analogue | CHEMBL320019)
Affinity DataKi:  0.430nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288625((S)-1-[3-(3-Fluoro-benzyl)-benzoyl]-pyrrolidine-2-...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288624((S)-1-[3-(2-Trifluoromethyl-phenylsulfanyl)-benzoy...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288619(Boropeptide | CHEMBL3037937)
Affinity DataKi:  0.460nMAssay Description:Compound was evaluated for the inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50289575(3-Methyl-2'-trifluoromethyl-biphenyl-4-carboxylic ...)
Affinity DataKi:  0.460nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288639((S)-1-[3-(2-Methylsulfanyl-benzyl)-benzoyl]-pyrrol...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288616((S)-1-[(3S,4R)-4-(3-Trifluoromethyl-phenyl)-pyrrol...)
Affinity DataKi:  0.5nMAssay Description:Compound was evaluated for the inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069929(Boropeptide analogue | CHEMBL103078)
Affinity DataKi:  0.530nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288622((S)-1-[3-(2-Methoxy-benzenesulfonyl)-benzoyl]-pyrr...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069938(Boropeptide analogue | CHEMBL103077)
Affinity DataKi:  0.580nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288405(CHEMBL95940 | N-[(1-Dihydroxyboranyl-4-guanidino-b...)
Affinity DataKi:  0.610nMAssay Description:Compound was tested in vitro for inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
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