TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by ChEMBL
Indiana University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of human FASN enoyl reductase activity using crotonyl CoA as substrate assessed as inhibition of substrate hydrolysis measured every 1 min...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ZAP70 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Yunnan University
Curated by ChEMBL
Yunnan University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of SRC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PKCdelta (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of ALK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of BRAF (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Yunnan University
Curated by ChEMBL
Yunnan University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of PDK1 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of FAK (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Yunnan University
Curated by ChEMBL
Yunnan University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of AKT1 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of TRKA (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of His6-tagged ENL YEATS domain (unknown origin) expressed in Escherichia coli BL21 DE3 and biotinylated H3K27ac peptide interaction using...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK3 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of TYK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Yunnan Research & Development Center For Natural Products
Curated by ChEMBL
Yunnan Research & Development Center For Natural Products
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hr...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Yunnan Research & Development Center For Natural Products
Curated by ChEMBL
Yunnan Research & Development Center For Natural Products
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in LDH release pretreated for 0.5 hrs f...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of GSK3b (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of Pyk2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of TRKA (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of TRKC (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of TRKA (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair