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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
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Affinity Data
Ki: 103nM
Assay Description:
Displacement of [3H]-prostaglandin D2 from human CRTh2 receptor expressed in CHO cells after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 103nM
Assay Description:
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to human prostaglandin D2 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to human thromboxane A2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 108nM
Assay Description:
Antagonist activity at CRTh2 receptor in human isolated eosinophil assessed as inhibition of DK-PGD2-induced shape change after 5 mins by flow cytome...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 108nM
Assay Description:
Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 565nM
Assay Description:
Antagonist activity at human CRTh2 receptor expressed in CHO cells assessed as inhibition of prostaglandin D2 and forskolin-induced cAMP accumulation...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human COX2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin G/H synthase 1
(Ovis aries (Sheep))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296851
(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of ovine COX1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI