Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50439435(CHEMBL2420700)Copy SMILESCopy InChI

Affinity DataIC50:  48nMAssay Description:Inhibition of CK1 delta (unknown origin) using PLSRTLpSVASLPGL as substrate after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50439435(CHEMBL2420700)Copy SMILESCopy InChI

Affinity DataIC50:  305nMAssay Description:Inhibition of CK1 epsilon (unknown origin) using PLSRTLpSVASLPGL as substrate after 85 mins by microplate reader analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50439435(CHEMBL2420700)Copy SMILESCopy InChI

Affinity DataIC50:  545nMAssay Description:Inhibition of human CK1 delta transfected in african green monkey cos7 cells after overnight incubation by whole cell assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI