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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Transcription initiation factor TFIID subunit 1
(Human)
Genentech
Curated by
ChEMBL
Ligand
BDBM321462
(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of recombinant His-tagged TAF1 bromodomain 2 (unknown origin) after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Chromatin remodeling regulator CECR2 [424-538]
(Human)
Genentech
US Patent
Ligand
BDBM321462
(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
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Affinity Data
IC50: 11nM
Assay Description:
His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Bromodomain-containing protein 9
(Human)
Genentech
Curated by
ChEMBL
Ligand
BDBM321462
(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
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Affinity Data
IC50: 1.40E+3nM
Assay Description:
Inhibition of recombinant His-tagged BRD9 (unknown origin) after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Chromatin remodeling regulator CECR2
(Human)
Genentech
Curated by
ChEMBL
Ligand
BDBM321462
(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
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Copy InChI
Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibition of recombinant His-tagged CECR2 (unknown origin) after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bromodomain-containing protein 4
(Human)
Genentech
Curated by
ChEMBL
Ligand
BDBM321462
(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
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Affinity Data
IC50: 5.10E+3nM
Assay Description:
Inhibition of recombinant His-tagged BRD4 bromodomain 1 (unknown origin) after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transcription initiation factor TFIID subunit 1
(Human)
Genentech
Curated by
ChEMBL
Ligand
BDBM321462
(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.60E+3nM
Assay Description:
Inhibition of recombinant His-tagged TAF1 bromodomain 1 (unknown origin) after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bromodomain-containing protein 4
(Human)
Genentech
Curated by
ChEMBL
Ligand
BDBM321462
(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of recombinant His-tagged BRD4 bromodomain 2 (unknown origin) after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI