Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant His-tagged TAF1 bromodomain 2 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50:  11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBromodomain-containing protein 9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant His-tagged BRD9 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant His-tagged CECR2 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain 1 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of recombinant His-tagged TAF1 bromodomain 1 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant His-tagged BRD4 bromodomain 2 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed