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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Purine nucleoside phosphorylase
(Rattus norvegicus)
Southern Research Institute
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
Ki: 5.00E+3nM
Assay Description:
Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)
More data for this Ligand-Target Pair
Target Info
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MMDB
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Target
Purine nucleoside phosphorylase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
Ki: 5.00E+3nM
Assay Description:
Competitive inhibition of human erythrocyte purine nucleoside phosphorylase assessed as inhibition of guanosine phosphorylysis after 30 mins by Linew...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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ChEBI
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Article
PubMed
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Target
Purine nucleoside phosphorylase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
Compound was tested for inhibition of purine nucleoside phosphorylase using human erythro lysate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
MMDB
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Article
PubMed
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Target
Shiga toxin subunit A
(Shigella dysenteriae)
TBA
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
IC50: 1.15E+4nM
Assay Description:
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as inhibition of Stx-induced cytotoxicity...
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Target Info
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Target
Ricin
(Ricinus communis)
University Of Texas
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
IC50: 9.00E+5nM
Assay Description:
Inhibitory concentration against Enzymatic A chain of ricin (RTA) using Artemia salina ribosomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
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B.MOAD
DrugBank
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ChEBI
CHEMBL
MMDB
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Target
Purine nucleoside phosphorylase
(Bos taurus (bovine))
University Of Warsaw
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
Kd: 120nM
Assay Description:
Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry
More data for this Ligand-Target Pair
Target Info
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MMDB
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Target
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
(Escherichia coli (strain K12))
St. Jude Children'S Research Hospital
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
Kd: 3.80E+4nM
Assay Description:
Binding affinity to GST-tagged Escherichia coli HPPK expressed in Escherichia coli by SPR assay based alternative equilibrium affinity method in pres...
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Target Info
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ChEBI
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Target
Purine nucleoside phosphorylase
(Bos taurus (bovine))
University Of Warsaw
Curated by
ChEMBL
Ligand
BDBM50200094
(2-amino-1,9-dihydro-6H-purin-6-one | CHEMBL219568 ...)
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Affinity Data
Kd: 160nM
Assay Description:
Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by fluorimetric titration analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI