Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 10 hits in this display
IC50: 46nMAssay Description:Inhibition of PARP3 (unknown origin) using activated DNA as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assayMore data for this Ligand-Target Pair
IC50: 222nMAssay Description:Inhibition of TNSK1/2-activated Wnt pathway in human DLD-1 TOPFlash/EF1a Renilla reporter cells after 24 hrs by Steady-Glo Luciferase assayMore data for this Ligand-Target Pair
EC50: 3nMAssay Description:Inhibition of PARP in human MDA-MB-468 cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
EC50: <18nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair