Found 4 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50499821'
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human PARP1 expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-...More data for this Ligand-Target Pair
Affinity DataEC50: 123nMAssay Description:Inhibition of PARP in multi-drug resistant human MCF7 cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based imag...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inhibition of PARP in human MDA-MB-468 cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <18nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair