Found 894 Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1B'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 166nMAssay Description:Competitive inhibition of GST-tagged DYRK1B (unknown origin) expressed in Escherichia coli BL21(DE3) by Lineweaver-Burk plot analysis in presence of ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 187nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 238nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 278nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 370nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 448nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 577nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 642nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 670nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 730nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 814nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 980nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 1.11E+3nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 1.13E+3nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 1.18E+3nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 1.45E+3nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 2.31E+3nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 4.40E+3nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.240nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.280nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:The substrate DYRKtide (synthetic peptide RRRFRPASPLRGPPK) was dissolved in freshly prepared Base Reaction Buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2,...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.590nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.699nMAssay Description:The substrate DYRKtide (synthetic peptide RRRFRPASPLRGPPK) was dissolved in freshly prepared Base Reaction Buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2,...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.852nMAssay Description:The substrate DYRKtide (synthetic peptide RRRFRPASPLRGPPK) was dissolved in freshly prepared Base Reaction Buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2,...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 0.967nMAssay Description:Inhibition of human DYRK1B using RRRFRPASPLRGPPK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.07nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DYRK1B using RRRFRPASPLRGPPK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair