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Found 7 of ic50 for monomerid = 50581147
TargetWD repeat-containing protein 5(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50:  29nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50:  780nMAssay Description:Inhibition of MLL1 (unknown origin) histamine methyltransferase activity assessed as inhibition of H3K4 methylation incubated for 30 mins by Alphascr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase KMT5A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SET8 (unknown origin) assessed as effect on H4K20 methylation incubated for 30 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as effect on H3R8/H4R3 methylation incubated for 30 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DOT1L (unknown origin) assessed as effect on H3K79 methylation incubated for 30 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of G9a (unknown origin) assessed as effect on H3K9 methylation incubated for 30 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as effect on H3K27 methylation incubated for 30 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed